History Medicine Science

Pandora's Lab takes us from opium's heyday as the pain reliever of choice to recognition of opioids as a major cause of death in the United States; from the rise of trans fats as the golden ingredient for tastier, cheaper food to the heart disease epidemic that followed; and from the cries to ban DDT for the sake of the environment to an epidemic-level rise in world malaria.

With its signature "DARE to keep kids off drugs" slogan and iconic t-shirts, DARE (Drug Abuse Resistance Education) was the most popular drug education program of the 1980s and 1990s. But behind the cultural phenomenon is the story of how DARE and other antidrug education programs brought the War on Drugs into schools and ensured that the velvet glove of antidrug education would be backed by the iron fist of rigorous policing and harsh sentencing.

For 200 years, a noble Venetian family has suffered from an inherited disease that strikes their members in middle age, stealing their sleep, eating holes in their brains, and ending their lives in a matter of months. In Papua New Guinea, a primitive tribe is nearly obliterated by a sickness whose chief symptom is uncontrollable laughter. Across Europe, millions of sheep rub their fleeces raw before collapsing. What these strange conditions share is their cause: prions.

With eloquent simplicity, one of the world's last Native American medicine men demonstrates how traditional tribal wisdom can help us maintain spiritual and physical health in today's world.

Out of the crucible of medical training, award-winning writer Terrence Holt shapes this stunning account of residency, the years-long ordeal in which doctors are made. "Amid all the mess and squalor of the hospital, with its blind random unraveling of lives", Internal Medicine finds the compassion from which doctors discover the strength to care.

In 1953, a 27-year-old factory worker named Henry Molaison - who suffered from severe epilepsy - received a radical new version of the then-common lobotomy, targeting the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry was left profoundly amnesic, unable to create long-term memories. Over the next 60 years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.

"Enthralling. Harrowing. Heartbreaking. And utterly redemptive. Lindsey Fitzharris hit this one out of the park." —Erik Larson, author of The Splendid and the Vile Lindsey Fitzharris, the award-winning author of The Butchering Art, presents the compelling, true story of a visionary surgeon who...

"Petkoff gives a flawless performance of this doctor/naturalist's memoir, conveying both his inquisitiveness and assuredness with aplomb." - AudioFile "A fascinating, lyrical book... Reisman's experiences in other cultures bring a richness and depth to The Unseen Body. The way he thinks about...

At the University of Wisconsin, Dr. Joshua Mezrich creates life from loss, transplanting organs from one body to another. In this intimate, profoundly moving work, he illuminates the extraordinary field of transplantation that enables this kind of miracle to happen every day.

A definitive history of mescaline that explores its mind-altering effects across cultures, from ancient America to Western modernity. Mescaline became a popular sensation in the mid-20th century through Aldous Huxley's The Doors of Perception, after which the word "psychedelic" was coined to describe it. Its story, however, extends deep into prehistory: The earliest Andean cultures depicted mescaline-containing cacti in their temples.

The Nobel laureate Otto Warburg was widely regarded in his day as one of the most important biochemists of the 20th century, a man whose research was integral to humanity’s understanding of cancer. He was also among the most despised figures in Nazi Germany. As a Jewish homosexual living openly with his male partner, Warburg represented all that the Third Reich abhorred. Yet Hitler and his top advisors dreaded cancer, and protected Warburg in the hope that he could cure it.

Little more than 100 years ago, maps of the world still boasted white space: places where no human had ever trod. Within a few short decades the most hostile of the world's environments had all been conquered. Likewise, in the 20th century, medicine transformed human life. Doctors took what was routinely fatal and made it survivable. As modernity brought us ever more into different kinds of extremes, doctors pushed the bounds of medical advances and human endurance. Extreme exploration challenged the body in ways that only the vanguard of science could answer.

Herbs have been used by humans throughout history—for cooking, medicine, rituals, and more. They are also a huge part of the modern world, from gardening, food, and cosmetics to medicines fighting diseases such as malaria. With expert knowledge, The Herb Book takes a close-up look at a wide range of herbs from around the world, showcasing their botanical characteristics, medicinal, cosmetic, and culinary properties and uses, and cultural impact on the lives of humans.

A History of the World in Six Plagues shows that throughout history, outbreaks of disease have been exacerbated by and gone on to further expand the racial, economic, and sociopolitical divides we allow to fester in times of good health. Princeton-trained historian Edna Bonhomme’s examination of humanity’s disastrous treatment of pandemic disease takes us across place and time from Port-au-Prince to Tanzania, and from plantation-era America to our modern COVID-19-scarred world to unravel shocking truths about the patterns of discrimination in the face of disease.

Cystic fibrosis was once a mysterious disease that killed infants and children. Now it could be the key to healing millions with genetic diseases of every type - from Alzheimer's and Parkinson's to diabetes and sickle cell anemia. Told from the perspectives of the patients, families, physicians, scientists, and philanthropists fighting on the front lines, Breath from Salt is a remarkable story of unlikely scientific and medical firsts, of setbacks and successes, and of people who refused to give up hope....

In 1968, Bruce Tucker, a Black man, went into Virginia’s top research hospital with a head injury, only to have his heart taken out of his body and put into the chest of a White businessman. Now, in The Organ Thieves, Pulitzer Prize-nominated journalist Chip Jones exposes the horrifying inequality surrounding Tucker’s death and how he was used as a human guinea pig without his family’s permission or knowledge.

In World War II, 59,000 women voluntarily risked their lives for their country as US Army nurses. For more than half a century these women's experiences remained untold, almost without reference in books, historical societies, or military archives. After years of research and hundreds of hours of interviews, Evelyn M. Monahan and Rosemary Neidel-Greenlee have created a dramatic narrative that at last brings to light the critical role that women played throughout the war.

Transcribed from the original lectures recorded at San Francisco State University in 1987, The Nature of Drugs series highlights Shulgin’s engaging lecture style peppered with illuminating anecdotes and amusing asides. Ostensibly taught as an introductory course on drugs and biochemistry, these books serve as both a historical record of Shulgin’s teaching style and the culmination of his philosophy on drugs, psychopharmacology, states of consciousness, and societal and individual freedoms pertaining to their use, both medicinal and exploratory.

Today, astonishing surgical breakthroughs are making limb transplants, face transplants, and a host of other previously undreamed-of operations possible. But getting here has not been a simple story of medical progress. In Blood and Guts, veteran science writer Richard Hollingham weaves a compelling narrative from the key moments in surgical history. We have a ringside seat in the operating theater of University College Hospital in London as world-renowned Victorian surgeon Robert Liston performs a remarkable amputation in 30 seconds - from first cut to final stitch.

America’s Bitter Pill is Steven Brill’s acclaimed book on how the Affordable Care Act, or Obamacare, was written, how it is being implemented, and, most important, how it is changing—and failing to change—the rampant abuses in the healthcare industry. It’s a fly-on-the-wall account of the titanic fight to pass a 961-page law aimed at fixing America’s largest, most dysfunctional industry. It’s a penetrating chronicle of how the profiteering that Brill first identified in his trailblazing Time magazine cover story continues, despite Obamacare.