Human Genetics

Once, we humans could only observe evolution. Suddenly, we had conquered it. And yet, in Life as We Made It, evolutionary biologist Beth Shapiro argues that - despite how amazing our new technologies are - our ability to alter the course of evolution isn’t new. What is new is that where once we shaped evolution through brute force, we can now do it as artisans. That power comes not a moment too soon. If we are going to survive in the next few centuries, we must revise the book of life.

As the oft-repeated and invariably accurate pearl of wisdom goes, a dog truly is man's best friend. For a long time, people have almost universally loved dogs, and it seems to have been that way for at least tens of thousands of years. When affection is abundantly and consistently expressed, this pure, unspoken, wholesome love is one that is very much requited, and then some. This bond can be demonstrated by the mere existence of pet keepers who unironically refer to themselves as “dog parents,” not merely “dog owners”.

In 2055, Lina Grahame was diagnosed with cancer. An experimental brain scan was meant to give her family peace of mind—insurance against the unknown. But when the system misfiled her consciousness, Lina was left dormant, forgotten, and reclassified as “simulation-grade.” Four centuries later, she wakes, not as the woman she was, but as a synthetic echo: fleshless, mislabeled, unacknowledged. The cities she wanders are alive with drones and faceless machines, but empty of people. The humans she longs for are gone—not extinguished, but voluntarily replaced.

2019 Best-Of Lists: 10 Best Science Books of the Year (Smithsonian Magazine) · Best Science Books of the Year (NPR's Science Friday) · Best Science and Technology Books from 2019” (Library Journal) An astute and timely examination of the re-emergence of scientific research into racial...

Fifty thousand years ago - merely a blip in evolutionary time - our Homo sapiens ancestors were competing for existence with several other human species, just as their precursors had done for millions of years. Yet something about our species distinguished it from the pack, and ultimately led to its survival while the rest became extinct. Just what was it that allowed Homo sapiens to become masters of the planet? Ian Tattersall, curator emeritus at the American Museum of Natural History, takes us deep into the fossil record to uncover what made humans so special.

What makes us human? Why are we the only animals who wear clothes, drive cars, trawl the internet, and fly helicopters on Mars? It’s all because we’ve learnt to talk, yet remarkably, we still don’t know how we did it. Speech! suggests an answer that’s been hiding in plain sight - the simple yet radical shift that turned our analog grunts and shrieks into words. But, its consequences are far from simple: being able to share ideas through language was an evolutionary tipping point - it allowed us to link up our minds.

"Eyeopening... Fascinating... may presage a paradigm shift in medicine.” —Kirkus Reviews (starred review) "Teeming with information and big ideas... Outstanding.” —Booklist (starred review) The origin of asthma, autism, Alzheimer's, allergies, cancer, heart disease, obesity, and...

Maternal instinct - the all-consuming, utterly selfless love that mothers lavish on their children - has long been assumed to be an innate, indeed defining element of a woman's nature. But is it? In this provocative, groundbreaking audiobook, renowned anthropologist (and mother) Sarah Blaffer Hrdy shares a radical new vision of motherhood and its crucial role in human evolution. Hrdy strips away stereotypes and gender-biased myths to demonstrate that traditional views of maternal behavior are essentially wishful thinking codified as objective observation.

When did the human species turn against the planet that we depend on for survival? Human industry and consumption of resources have altered the climate, polluted the water and soil, destroyed ecosystems, and rendered many species extinct, vastly increasing the likelihood of an ecological catastrophe. How did humankind come to rule nature to such an extent? To regard the planet's resources and creatures as ours for the taking? To find ourselves on a seemingly relentless path toward ecocide?

Who are we, and how did we get here? These are two of the most fundamental and far-reaching questions facing scientists and cosmologists alike and have rested at the center of human intellectual endeavor since its beginning. They are questions that stretch across numerous disciplines. Philosophy, theology, evolutionary biology, and mathematics are just some of the fields looking to explain the emergence of human life.

This new book by Spencer Wells, the internationally known geneticist, anthropologist, author, and director of the Genographic Project, focuses on the seminal event in human history: mankind's decision to become farmers rather than hunter-gatherers.

Best-selling author Brian Fagan brings early humans out of the deep freeze with his trademark mix of erudition, cutting-edge science, and vivid storytelling. Cro-Magnon reveals human society in its infancy, facing enormous environmental challenges - including a rival species of humans, the Neanderthals. For ten millennia, Cro-Magnons lived side by side with Neanderthals, an encounter that Fagan fills with drama.

How four tools enabled humanity to control its destiny What enabled us to go from simple stone tools to smartphones? How did bands of hunter-gatherers evolve into multinational empires? Listeners of Sapiens will say a cognitive revolution - a dramatic evolutionary change that altered our brains, turning primitive humans into modern ones - caused a cultural explosion. In Transcendence, Gaia Vince argues instead that modern humans are the product of a nuanced coevolution of our genes, environment, and culture that goes back into deep time.

For five centuries, human life has been restricted to Earth, while posthuman descendants called alloys freely explore the galaxy. But when the Earthlike planet of Meru is discovered, two unlikely companions venture forth to test the habitability of this unoccupied new world and the future of human-alloy relations. For Jayanthi, the adopted human child of alloy parents, it’s an opportunity to rectify the ancient reputation of her species as avaricious and destructive, and to give humanity a new place in the universe.

The burgeoning new science of epigenetics offers a cornucopia of insights - some comforting, some frightening. For example, the male fetus may be especially vulnerable to certain common chemicals in our environment, in ways that damage not only his own sperm but also the sperm of his sons. And it’s epigenetics that causes identical twins to vary widely in their susceptibility to dementia and cancer. But here’s the good news: unlike mutations, epigenetic effects are reversible. Indeed, epigenetic engineering is the future of medicine.

Binary is the ultimate guide for understanding and dismantling the sex spectrum, the new cultural belief that sex exists on a continuum and that male and female are social constructs. By analyzing its 10 most popular arguments, Zachary A. Elliott reveals how the tenets of the sex spectrum deny evolution, development, and genetics. Using the primary biology literature, the book provides the listener with a comprehensive scientific understanding of how the two sexes are universal phenomena and how complex genetic networks consistently result in a simple yet profound outcome: male or female.

Generations have been taught that evolution implies there is no overarching purpose to our existence. Some scientists take this logic one step further, suggesting that evolution is intrinsically atheistic and goes against the concept of God. But is this true? By integrating emerging principles from a variety of scientific disciplines—ranging from evolutionary biology to psychology—Yale Professor Samuel Wilkinson provides a framework of evolution that implies not only that there is an overarching purpose to our existence, but what this purpose is.

From the former editor of Slate and CEO of Atlas Obscura comes the unbelievable story of “the Nobel Prize sperm bank” and the children it produced—“a superb book about the quest for genius and, ultimately, family” (Malcolm Gladwell, author of The Tipping Point and Talking to Strangers)...

Approximately 200,000 years ago, as modern humans began to radiate out from their evolutionary birthplace in Africa, Neanderthals were already thriving in Europe - descendants of a much earlier migration of the African genus Homo. But when modern humans eventually made their way to Europe 45,000 years ago, Neanderthals suddenly vanished.

The idea of a missing link between humanity and our animal ancestors predates evolution and popular science and actually has religious roots in the deist concept of the Great Chain of Being. Yet, the metaphor has lodged itself in the contemporary imagination, and new fossil discoveries are often hailed in headlines as revealing the elusive transitional step, the moment when we stopped being "animal" and started being "human". In The Accidental Species, Henry Gee, longtime paleontology editor at Nature, takes aim at this misleading notion.