Human Genetics

Homo sapiens emerged as a species about 200,000 years ago and soon—with fire, simple tools, and an egalitarian social system—we inhabited every continent. But now our infinitely elaborated tools and our highly non-egalitarian social system threaten sustainability. Many at the bottom lose the desire to live, committing suicide or succumbing to drugs, alcohol, and obesity. What is Health? explains from the bottom up—molecules to society—how we reached this point.

At a conference in Hong Kong in November 2018, Dr. He Jiankui announced that he had created the first genetically modified babies - twin girls named Lulu and Nana - sending shockwaves around the world. A year later, a Chinese court sentenced Dr. He to three years in prison for "illegal medical practice". As scientists elsewhere start to catch up with China's vast genetic research program, gene editing is fueling an innovation economy that threatens to widen racial and economic inequality. Fundamental questions about science, health, and social justice are at stake.

As biologist Jeremy Griffith explains in The Interview (which psychiatrist Professor Harry Prosen described as the most important interview of all time), while we humans lacked the explanation for our 2-million-year corrupted human condition we had no choice but to deny that our distant ape ancestors lived in a state of cooperative and loving innocence.

Over the last three million years or so, our lineage has diverged sharply from those of our great ape relatives. Change has been rapid (in evolutionary terms) and pervasive. In The Evolved Apprentice, Kim Sterelny argues that the divergence stems from the fact humans gradually came to enrich the learning environment of the next generation. He develops a new theory of the evolution of human cognition and human social life that emphasizes the gradual evolution of information-sharing practices across generations and how these practices transformed human minds and social lives.

In this engaging exploration, archaeologist Ian Hodder departs from the two prevailing modes of thought about human evolution: the older idea of constant advancement toward a civilized ideal and the newer one of a directionless process of natural selection. Instead, he proposes a theory of human evolution and history based on "entanglement," the ever-increasing mutual dependency between humans and things.

Over a decade ago, as the Human Genome Project completed its mapping of the entire human genome, hopes ran high that we would rapidly be able to use our knowledge of human genes to tackle many inherited diseases, and understand what makes us unique among animals. But things didn't turn out that way.

The Project 99 experiments continue to find answers about themselves as they dig deeper into their past. Who are they? What are they supposed to be? As they keep searching, they find their chimera. She was where they were all created from. Does she have the answers they are looking for? And what else does Project 99 have in store for them?

Mit Milliarden auf meinem Konto und meiner eigenen Risikokapitalgesellschaft bin ich der lebende amerikanische Traum. Mein einziges Problem? Nach einem Autounfall leidet meine Mutter an Gedächtnisproblemen.

Nicolelis undertakes the first attempt to explain the entirety of human history, culture, and civilization based on a series of recently uncovered key principles of brain function. This new cosmology is centered around three fundamental properties of the human brain: its insurmountable malleability to adapt and learn; its exquisite ability to allow multiple individuals to synchronize their minds around a task, goal, or belief; and its incomparable capacity for abstraction.

It is widely understood that Charles Darwin’s theory of evolution completely revolutionized the study of biology. Yet, according to David Sloan Wilson, the Darwinian revolution won’t be truly complete until it is applied more broadly—to everything associated with the words “human,”...

They once thought dark energy was the ultimate power in the universe. They were mistaken. And now a desperate race is underway to be the first to discover how The Formation helped create life in the universe. But with the power to create life also comes the power to destroy it. This was power even the wise and ancient Aris knew was too great for them to possess. Now imagine what it could do in the hands of a mere mortal...such as Adam Cain.

The sixth "mass extinction event" in the history of planet Earth is currently under way, with over two hundred species dying off every day. The cause of this seismic event is also the source of the single biggest threat to human life: our own inventions. But for all our talk about sea levels and biotechnology, do we really know what our future will actually look like? Will our immune systems be attacked by so-called super bugs, always evolving, and more easily spread than ever? Will the disappearance of numerous species cripple the biosphere?

In humanity’s more than 100,000 year history, we have evolved from vulnerable creatures clawing sustenance from Earth to a sophisticated global society manipulating every inch of it. In short, we have become the dominant animal. Why, then, are we creating a world that threatens our own species? What can we do to change the current trajectory toward more climate change, increased famine, and epidemic disease?

From the former editor of Slate and CEO of Atlas Obscura comes the unbelievable story of “the Nobel Prize sperm bank” and the children it produced—“a superb book about the quest for genius and, ultimately, family” (Malcolm Gladwell, author of The Tipping Point and Talking to...

Humans are awesome. Our brains are gigantic, seven times larger than they should be for the size of our bodies. The human brain uses 25 percent of all the energy the body requires each day. And it became enormous in a very short amount of time in evolution, allowing us to leave our cousins, the great apes, behind. So the human brain is special, right? Wrong, according to Suzana Herculano-Houzel. Humans have developed cognitive abilities that outstrip those of all other animals but not because we are evolutionary outliers.

AD 2107: A generation ago, Earth and the cislunar colonies banned genetic and cybernetic modifications. But out in the Asteroid Belt, anything goes. Dozens of flourishing space habitats are spawning exotic new societies and strange new varieties of humans. It’s a volatile situation that threatens the peace and stability of the entire solar system.

The Human Blend is a science-fiction adventure centered around a group of thieves living in a future where physical alterations and enhancements are a common occurrence. If you could take on a body with any features you wanted, what would it look like? And what would you do with them - human or otherwise?

In the new essays collected here, an interdisciplinary group of scholars asks age-old questions about the nature and well-being of humans in the context of a revolutionary new biotechnology - one that has the potential to change the genetic make-up of both existing people and future generations. Welcoming listeners who study related issues and those not yet familiar with the formal study of bioethics, the authors of these essays open up a conversation about the ethics of gene editing.

This dynamic chronicle of the race to find the "missing links" between humans and apes transports readers into the highly competitive world of fossil hunting and into the lives of the ambitious scientists intent on pinpointing the dawn of humankind. The quest to find where and when the earliest human ancestors first appeared is one of the most exciting and challenging of all scientific pursuits.

What makes us human? Why are we the only animals who wear clothes, drive cars, trawl the internet, and fly helicopters on Mars? It’s all because we’ve learnt to talk, yet remarkably, we still don’t know how we did it. Speech! suggests an answer that’s been hiding in plain sight - the simple yet radical shift that turned our analog grunts and shrieks into words. But, its consequences are far from simple: being able to share ideas through language was an evolutionary tipping point - it allowed us to link up our minds.