Medical History

More than four hundred abandoned suitcases filled with patients’ belongings were found when Willard Psychiatric Center closed in 1995 after 125 years of operation. They are skillfully examined here and compared to the written record to create a moving—and devastating—group portrait of twentieth-century American psychiatric care.

In this partially autobiographical work, best-selling author Lewis Thomas offers insights on subjects as wide-ranging as gender differences, how it feels to be a patient, human vs. computer intelligence, the future of cancer research, and the longevity of the planet—interspersing all with charming anecdotes about his family, his colleagues and himself.

In the quarter century that Victoria Sweet has been a doctor, "health care" has replaced medicine, "providers" (vastly outnumbered by administrators) look at their laptops more than at their patients, and the ruthless pursuit of efficiency has vanquished not only trust and intimacy but also, often, the effectiveness of treatment. Victoria Sweet knows that there is an alternative way, because she has lived and practiced it. In her new book, she reflects with compassion, wit, and profound insight.

For 200 years, a noble Venetian family has suffered from an inherited disease that strikes their members in middle age, stealing their sleep, eating holes in their brains, and ending their lives in a matter of months. In Papua New Guinea, a primitive tribe is nearly obliterated by a sickness whose chief symptom is uncontrollable laughter. Across Europe, millions of sheep rub their fleeces raw before collapsing. What these strange conditions share is their cause: prions.

Pandemics have afflicted human civilizations throughout history, yet these health crises have also led to progress in medicine and society that improved people’s lives. History shows that scientific innovation often proceeds from the collaboration of researchers across disciplines, nations, and institutions.

By investigating thousands of descriptions of epidemics reaching back before the fifth-century-BCE Plague of Athens to the distrust and violence that erupted with Ebola in 2014, Epidemics challenges a dominant hypothesis in the study of epidemics, that invariably across time and space, epidemics provoked hatred, blaming of the "other", and victimizing bearers of epidemic diseases, particularly when diseases were mysterious, without known cures or preventive measures.

In 1953, a 27-year-old factory worker named Henry Molaison - who suffered from severe epilepsy - received a radical new version of the then-common lobotomy, targeting the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry was left profoundly amnesic, unable to create long-term memories. Over the next 60 years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.

In 1932, the US Public Health Service recruited 623 African American men from Macon County, Alabama, for a study of "the effects of untreated syphilis in the Negro male". For the next 40 years - even after the development of penicillin, the cure for syphilis - these men were denied medical care for this potentially fatal disease.

Considering herself unsuitable for any other contribution to the war effort, Monica Dickens opts for nursing, imagining herself gliding through the wards, serene in a pure white halo cap. On enrolment, however, she is promptly stripped of all illusions. Intelligent and headstrong, Monica struggles to submit to the iron rule of the Matron and toils over the mountains of menial work that are a trainee's lot. But there are friends among the staff and patients, night-time escapades to dances with dashing army men and her secret writing project to keep her going.

The search to find medicines is as old as disease, which is to say as old as the human race. Through serendipity - by chewing, brewing, and snorting - some Neolithic souls discovered opium, alcohol, snakeroot, juniper, frankincense, and other helpful substances. Ötzi the Iceman, the 5,000-year-old hunter frozen in the Italian Alps, was found to have whipworms in his intestines and Bronze Age medicine, a worm-killing birch fungus, knotted to his leggings.

The Aging Revolution is the story of Butler and his disciples: women and men who saw older distressed adults in hospitals and homes, and worse: being ignored by most of the medical establishment. These revolutionaries could not ignore the suffering, and they set out—individually and collectively—to create entirely new ways of caring for aging adults to ease their suffering and improve their quality and length of life.

Ingrassia lost his mother, two sisters, brother, and nephew to cancer—different cancers developing at different points throughout their lives. And while highly unusual, his family is not the only one to wonder whether their heartbreak is the result of unbelievable bad luck, or if there might be another explanation. Through meticulous research and riveting storytelling, Ingrassia takes us from the 1960s—when Dr. Frederick Pei Li and Dr. Joseph Fraumeni Jr. first met, not yet knowing that they would help make a groundbreaking discovery that would affect cancer patients for decades to come.

In this new book, Kidder gives us the superb story of a hero for our time. Strength in What Remains is a wonderfully written, inspiring account of one man’s remarkable American journey and of the ordinary people who helped him–a brilliant testament to the power of will and of second chances.

From the 15th to the mid-19th centuries, scurvy caused more deaths at sea than storms, shipwrecks, combat, and all other diseases combined. The cure for scurvy ranks among the greatest of military successes, yet its impact on history has mostly been ignored. In this book, Stephen R. Brown delivers a lively recounting of how three determined individuals overcame the constraints of 18th century thinking to solve the greatest medical mystery of their era. Brimming with tales of ships, sailors, and bureaucracy, Brown presents a vivid picture of life aboard the ship during the age of sail.

When a waiting world learned on April 12, 1955, that Jonas Salk had successfully created a vaccine to prevent poliomyelitis, he became a hero overnight. Born in a New York tenement, humble in manner, Salk had all the makings of a 20th-century icon - a knight in a white coat. In the wake of his achievement, he received a staggering number of awards and honors; for years his name ranked with Gandhi and Churchill on lists of the most revered people.

Born in 1966 with a congenital heart defect known as the tetralogy of Fallot, Gabriel Brownstein entered the world just as doctors were learning to operate on conditions like his. He received a life-saving surgery at five years old, and since then has ridden wave after wave of medical innovation, a series of interventions that have kept his heart beating. The Open Heart Club is both a memoir of a life on the edge of medicine's reach and a history of the remarkable people who have made such a life possible.

Larry Brilliant's life journey has led him on a purposeful path across continents and countercultural movements, marching arm in arm with the men and women who defined a generation. A man who has always been in the right place at the right time, Brilliant has engaged with some of the most prominent thought leaders, spiritual masters, heroes, and icons in the world, including Neem Karoli Baba (Maharajji), Martin Luther King Jr., Steve Jobs, Mikhail Gorbachev, Wavy Gravy, the Grateful Dead, the Dalai Lama, and Barack Obama.

Was Andy Warhol a hoarder? Did Einstein have autism? Was Frank Lloyd Wright a narcissist? In this surprising, inventive, and meticulously researched look at the evolution of mental health, acclaimed health and science journalist Claudia Kalb gives listeners a glimpse into the lives of high-profile historic figures through the lens of modern psychology, weaving groundbreaking research into biographical narratives that are deeply embedded in our culture.

Human history hinges on the battle to confront our most dangerous enemies—the half-dozen diseases responsible for killing almost all of mankind. The story of our medical triumphs reveals an inspiring tapestry of human achievement, but the journey was far from smooth. It is a tale replete with dramatic episodes as spellbinding as any blockbuster Hollywood movie. In The Masters of Medicine, Dr. Andrew Lam, an award-winning author and retinal surgeon, distills the long arc of medical progress down to the crucial moments that were responsible for the world's greatest medical miracles.

Americans are in the midst of a world-historic drug binge. Opiates, amphetamines, benzodiazepines, marijuana, antidepressants, antipsychotics—across the board, consumption has shot up in the twenty-first century. At the same time, the United States is home to the largest prison system in the world, justified in part by a now zombified "war" on drugs. How did we get here?