Medical History

From insulin comas and lobotomy to incarceration and exile, Walter Brown chronicles the troubling history of the diagnosis and (often ineffective) treatment of bipolar disorder through the centuries, before the publication of a groundbreaking research paper in 1949. Cade's "Lithium Salts in the Treatment of Psychotic Excitement" described, for the first time, lithium's astonishing efficacy at both treating and preventing the recurrence of manic-depressive episodes, and would eventually transform the lives of patients, pharmaceutical researchers, and practicing physicians worldwide.

Crypto, decentralized blockchains, NFTs, and the ownership economy of web3 hold the future of healthcare. Discover how the metaverse provides innovative business models that are poised to revolutionize the way society approaches health. Wealthcare envisions what healthcare and wellness may look like when accidental wellness is a thing of the past. As web3 technology reshapes finance, supply chain, social media, and other industries, Wealthcare presents a clear case for including healthcare privacy and innovation within this new reality.

The idea that medicine is gender-neutral is a myth. This isn't inflammatory rhetoric; it's simply true. From the way pain is felt, to how heart attacks are diagnosed, to the very role society plays in the health of the body, the medical landscape in place today is one that was designed for, and by, men. This audiobook is about all the ways medicine is not gender-neutral, from research to treatment to diagnosis. Throughout history, flawed mindsets have paved the way for sub-par treatment, and the prevailing attitudes that exist today have had terrible repercussions for women.

In 1953, a 27-year-old factory worker named Henry Molaison - who suffered from severe epilepsy - received a radical new version of the then-common lobotomy, targeting the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry was left profoundly amnesic, unable to create long-term memories. Over the next 60 years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.

In World War II, 59,000 women voluntarily risked their lives for their country as US Army nurses. For more than half a century these women's experiences remained untold, almost without reference in books, historical societies, or military archives. After years of research and hundreds of hours of interviews, Evelyn M. Monahan and Rosemary Neidel-Greenlee have created a dramatic narrative that at last brings to light the critical role that women played throughout the war.

In 1932, the US Public Health Service recruited 623 African American men from Macon County, Alabama, for a study of "the effects of untreated syphilis in the Negro male". For the next 40 years - even after the development of penicillin, the cure for syphilis - these men were denied medical care for this potentially fatal disease.

For centuries, the human heart seemed beyond our understanding: an inscrutable shuddering mass that was somehow the driver of emotion and the seat of the soul. As cardiologist and best-selling author Sandeep Jauhar tells in The Heart, it was only recently that we demolished age-old taboos and devised the transformative procedures that changed the way we live. Deftly alternating between historical episodes and his own work, Jauhar tells the colorful and little known story of the doctors who risked their careers and the patients who risked their lives to know and heal our most vital organ.

Cystic fibrosis was once a mysterious disease that killed infants and children. Now it could be the key to healing millions with genetic diseases of every type - from Alzheimer's and Parkinson's to diabetes and sickle cell anemia. Told from the perspectives of the patients, families, physicians, scientists, and philanthropists fighting on the front lines, Breath from Salt is a remarkable story of unlikely scientific and medical firsts, of setbacks and successes, and of people who refused to give up hope....

In 1907 Sigmund Freud and Carl Gustav Jung began what promised to be both a momentous collaboration and the deepest friendship of each man's life. Six years later they were bitter antagonists, locked in a savage struggle that was as much personal and emotional as it was theoretical and professional. In between them stood a young woman named Sabina Spielrein, who had been both patient and lover to Jung and colleague and confidante to Freud before going on to become an innovative psychoanalyst herself.

Jeanne Marie Laskas first met the young forensic pathologist Dr. Bennet Omalu in 2009, while reporting a story for GQ that would go on to inspire the movie Concussion. Omalu told her about a day in September 2002, when, in a dingy morgue in downtown Pittsburgh, he picked up a scalpel and made a discovery that would rattle America in ways he’d never intended. Omalu was new to America, chasing the dream, a deeply spiritual man escaping the wounds of civil war in Nigeria.

Stuart Jamieson's story is the story of four decades of advances in heart surgery. Taut, elegantly crafted, and ever-attentive to the patients for whom he was the last best chance, Close to the Sun is an adventurous, riveting account based on the experience of over 40,000 heart surgeries, where everything was on the line every moment in the O.R.

It wasn’t supposed to be this hard. If America could send a man to the moon, shouldn’t the best surgeons in the world be able to build an artificial heart? In Ticker, Texas Monthly executive editor and two time National Magazine Award winner Mimi Swartz shows just how complex and difficult it can be to replicate one of nature’s greatest creations. Part investigative journalism, part medical mystery, Ticker is a dazzling story of modern innovation, recounting 50 years of false starts, abysmal failures, and miraculous triumphs.

12-year-old Isabella, a French princess marries the King of England - only to discover he has a terrible secret. Ten long years later she is in utter despair - does she submit to a lifetime of solitude and a spiritual death - or seize her destiny and take the throne of England for herself? Isabella is just twelve years old when she marries Edward II of England. For the young princess it is love at first sight - but Edward has a terrible secret that threatens to tear their marriage - and England apart.

In the last half of the twentieth century, Don Thomas discovered a cure for every marrow-based disease—like leukemia, lymphoma, and sickle-cell anemia—forever changing treatment for some of the deadliest illnesses. His feats were extraordinary, earning him a Nobel Prize, and the cascade of treatments he inspired have reshaped and will continue to reshape the practice of clinical medicine. Yet no one has ever written Thomas’s courageous story.Dr. Frederick R. Appelbaum, a member of Thomas’s research team, does so for the first time.

In 1959, a Cincinnati pharmaceutical firm, the William S. Merrell Company, quietly began distributing samples of an exciting new wonder drug already popular around the world. Touted as a sedative without risks, thalidomide was handed out freely, under the guise of clinical trials, by doctors who believed approval by the Food and Drug Administration was imminent. But in 1960, when the application for thalidomide landed on the desk of FDA medical reviewer Frances Kelsey, she quickly grew suspicious.

In Origin Story, medical historian Howard Markel recounts the two-year period (1858 to 1860) of Darwin's writing of On the Origin of Species through its spectacular success and controversy. Simultaneously, Markel delves into the mysterious health symptoms Darwin developed, combing the literature to emerge with a cogent diagnosis of a case that has long fascinated medical historians.

How and why did humans begin to treat sick and injured animals? And how did those practices, and the associated attitudes, evolve from prehistory to the present day? To answer these questions, Dr. Schott shares stories of twenty-two different animal healers and veterinarians from across eras and continents, examining the always fascinating, often unexpected, and sometimes hilarious veterinary methods employed by these people and their colleagues. But at the heart of the tale lies the evolution of the human-animal bond, which has been more cyclical than linear.

There Plant Eyes probes the ways in which blindness has shaped our ocularcentric culture, challenging deeply ingrained ideas about what it means to be “blind”. For millennia, blind­ness has been used to signify such things as thoughtlessness (“blind faith”), irrationality (“blind rage”), and unconsciousness (“blind evolution”). But at the same time, blind people have been othered as the recipients of special powers as compensation for lost sight (from the poetic gifts of John Milton to the heightened senses of the comic book hero Daredevil).

Jede Krankheit und jeder Mensch haben das Potential, Medizingeschichte zu schreiben. Seit Hunderten von Jahren ergründen Ärzte und Ärztinnen auf der ganzen Welt die Geheimnisse der Medizin, indem sie sich echte Fälle ansehen. Autor und Arzt Roy Benaroch hat für uns spannende Fälle der Medizingeschichte gesammelt, in denen bekannte Persönlichkeiten der Weltgeschichte als mysteriöser Patient oder Patientin vor uns stehen.

In the early 1800s, a century before there was any concept of the gene, physicians in insane asylums began to record causes of madness in their admission books. Almost from the beginning, they pointed to heredity as the most important of these causes. As doctors and state officials steadily lost faith in the capacity of asylum care to stem the terrible increase of insanity, they began emphasizing the need to curb the reproduction of the insane. They became obsessed with identifying weak or tainted families and anticipating the outcomes of their marriages.