Orphaned during her passage from Ireland, young, white Lavinia arrives on the steps of the kitchen house and is placed, as an indentured servant, under the care of Belle, the master's illegitimate slave daughter. Lavinia learns to cook, clean, and serve food while guided by the quiet strength and love of her new family. In time Lavinia is accepted into the world of the big house, caring for the master's opium-addicted wife and befriending his dangerous yet protective son. She attempts to straddle the worlds of the kitchen and big house, but her skin color will forever set her apart.

According to Confucius, “an educated woman is a worthless woman,” but Tan Yunxian—born into an elite family, yet haunted by death, separations, and loneliness—is being raised by her grandparents to be of use. Her grandmother is one of only a handful of female doctors in China, and she teaches Yunxian the pillars of Chinese medicine, the Four Examinations—looking, listening, touching, and asking—something a man can never do with a female patient.

Maine, 1789: When the Kennebec River freezes, entombing a man in the ice, Martha Ballard is summoned to examine the body and determine cause of death. As a midwife and healer, she is privy to much of what goes on behind closed doors in Hallowell. Her diary is a record of every birth and death, crime and debacle that unfolds in the close-knit community. Months earlier, Martha documented the details of an alleged rape committed by two of the town’s most respected gentlemen—one of whom has now been found dead in the ice.

California, 1938—When she loses her parents in an accident, sixteen-year-old Rosanne is taken in by the owners of the vineyard where she has lived her whole life as the vinedresser’s daughter. She moves into Celine and Truman Calvert’s spacious house with a secret, however—Rosie sees colors when she hears sound. She promised her mother she’d never reveal her little-understood ability to anyone, but the weight of her isolation and grief prove too much for her. Driven by her loneliness she not only breaks the vow to her mother, but in a desperate moment lets down her guard and ends up pregnant.

Ernt Allbright, a former POW, comes home from the Vietnam war a changed and volatile man. When he loses yet another job, he makes an impulsive decision: He will move his family north, to Alaska, where they will live off the grid in America’s last true frontier.