A construction project beneath the National Mall reveals a dark secret dating back to the Civil War, something buried by a cabal of scientists, led by Alexander Graham Bell, who helped found the Smithsonian Institution. It is a cache of bones, preserved in amber, protecting a wonder like no other, the very secret of life after death. But such a prize is guarded by a horror out of the ancient past, a horror that still lives in the marrow of those bones - and is now free again.

To save the world and our future, Sigma Force must embark on a dangerous odyssey into an ancient past whose horrors are all too present in this pause-resisting thriller from number-one New York Times best-selling author James Rollins that combines cutting-edge science, historical mystery, mythology, and pulse-pounding action.

If the biblical plagues of Egypt truly happened—could they happen again—on a global scale? Two years after vanishing into the Sudanese desert, Professor Harold McCabe comes stumbling out of the sands, but he dies before he can tell his story. Then an autopsy uncovers a bizarre corruption: someone had begun to mummify the professor's body—while he was still alive. Subsequently, the medical team who had performed the man's autopsy has fallen ill with an unknown disease. Fearing the worst, a colleague of the professor reaches out to Painter Crowe, the director of Sigma Force. The call is urgent, for Professor McCabe had vanished into the desert while searching for proof of the ten plagues of Moses.

A series of strange events throws the world into turmoil. As a manned Chinese rocket explodes upon launch, three American astronauts, each separated by thousands of miles, are murdered. Then an archaeologist in Croatia uncovers a new cavern system that reveals elaborate primitive paintings by a tribe of Neanderthals.

A conclave to select the pope's replacement is about to begin. Cardinals are beginning to arrive at the Vatican, but one has fled Rome for Malta in search of a document that dates back to the fourth century. Former Justice Department operative Cotton Malone is at Lake Como, Italy, on the trail of letters between Winston Churchill and Benito Mussolini that disappeared in 1945 and could rewrite history. But someone else seems to be after the same letters, and when Malone obtains and then loses them, he’s plunged into a hunt that draws the attention of the legendary Knights of Malta.

Galilee, 1025. A cunning Templar knight uncovers a holy treasure: the Bachal Isu - the staff of Jesus Christ - a priceless icon that holds a mysterious and terrifying power that will forever change humanity if unleashed. A millennium later, Somali pirates hijack a yacht off the coast of the Horn of Africa, kidnapping a young pregnant American woman and brutally killing her husband. Painter Crowe and his Sigma team are enlisted for the top secret rescue mission.

A remote military research station sends out a frantic distress call, ending with a chilling final command: Kill us all! Personnel from the neighboring base rush in to discover everyone already dead - and not just the scientists, but every living thing for 50 square miles is annihilated: every animal, plant, and insect, even bacteria. The land is entirely sterile - and the blight is spreading. To halt the inevitable, Commander Gray Pierce and Sigma must unravel a threat that rises out of the distant past.

After an overhaul of leadership at the FBI's New York field office, A. X. L. Pendergast is abruptly forced to accept an unthinkable condition of continued employment: the famously rogue agent must now work with a partner. Pendergast and his new teammate, junior agent Coldmoon, are assigned to Miami Beach, where a rash of killings by a bloodthirsty psychopath are distinguished by a confounding M.O.: cutting out the hearts of his victims and leaving them - along with cryptic handwritten letters - at local gravestones, unconnected save in one bizarre way.

An earthquake in Masada, Israel, kills hundreds and reveals a tomb buried in the heart of the mountain. A trio of investigators - Sergeant Jordan Stone, a military forensic expert; Father Rhun Korza, a Vatican priest; and Dr. Erin Granger, a brilliant but disillusioned archaeologist - are sent to explore the macabre discovery, a subterranean temple holding the crucified body of a mummified girl. But a brutal attack at the site sets the three on the run, thrusting them into a race to recover what was once preserved in the tomb's sarcophagus: a book rumored to have been written by Christ's own hand....

At Princeton University, a famed geneticist dies inside a biohazard lab. In Rome, a Vatican archaeologist is found dead in St. Peter's Basilica. In Africa, a U.S. senator's son is slain outside a Red Cross camp. The three murders on three continents bear a horrifying connection: all the victims are marked by a Druidic pagan cross burned into their flesh. The bizarre murders thrust Commander Gray Pierce and Sigma Force into a race against time to solve a riddle going back centuries.

High in Nepal, a monastery erupts with savagery and madness. Deep in a German mine, abomination wears the innocent face of a child. Hidden in the jungles of Africa, experiments rooted in a dark past have found fertile ground again.

An inexplicable explosion rocks the antiquities collection of a London museum and the race begins to determine how it happened, why it happened, and what it means. Lady Kara Kensington's family paid a high price in money and blood to found the gallery that now lies in ruins. Her search for answers leads Kara and her friend Safia al-Maaz, the gallery's curator, into a world they never dreamed existed.

After former Justice Department agent Cotton Malone witnesses the theft of one of them, he learns from his old boss, Stephanie Nelle, that a private auction is about to be held where incriminating information on the president of Poland will be offered to the highest bidder - blackmail that both the United States and Russia want, but for vastly different reasons. The price of admission to that auction is one of the relics, so Malone is first sent to a castle in Poland to steal the Holy Lance, a 1,000-year-old spear sacred to not only Christians but to the Polish people.

In Washington, D.C., a homeless man dies in Commander Gray Pierce's arms, shot by an assassin's bullet. But the death leaves behind a greater mystery: a bloody coin found clutched in the dead man's hand, an ancient relic that can be traced back to the Greek Oracle of Delphi.

Something is amiss on the open waters of the Indian Ocean. When a group of adventurers investigates a luminescent pool of water, they come in contact with a deadly organism risen from the depths. To combat this threat, Sigma Force races across the globe searching for a cure that may be hidden within humanity’s genetic code. But elements of an ancient conspiracy want the plague to spread, and they have a mole entrenched within Sigma Force.