Meghan Michaels is trying to find balance between being a single mom and working full time as an ICU nurse, when a patient named Caitlin arrives in her ward with a traumatic brain injury. They say she jumped from a bridge and plunged over twenty feet to the train tracks below.

Life can change in an instant. For Ryan and Karen Lane, it happens on the morning they discover their 12-year-old daughter’s window open, their beloved Maddie missing from her bed. Police investigate. Suspicions swirl. A teenage boy admits he was outside her bedroom window the night she disappeared. A halfway house for convicts recently opened in the neighborhood. The Lane family is thrown into turmoil, and then the detectives turn their sights on them.

Grace Evans, an overworked New Yorker looking for a total escape from her busy life, books an Airbnb on a ranch in the middle of Wyoming. When she arrives at the idyllic getaway, she’s pleased to find that the owner is a handsome man by the name of Calvin Wells—and he’s eager to introduce her to his easygoing way of life. But there are things Grace discovers that she’s not too pleased about: a lack of cell phone service. A missing woman. And a feeling that something isn’t right with the ranch.

Olivia Bender designs exquisite home interiors that satisfy the most demanding clients. But her own deepest desire can’t be fulfilled by marble counters or the perfect rug. She desperately wants to be a mother. Fertility treatments and IVF keep failing. And just when she feels she’s at her lowest point, the police deliver shocking news to Olivia and her husband, Park. DNA results show that the prime suspect in a murder investigation is Park’s son. Olivia is relieved, knowing this is a mistake. Despite their desire, the Benders don’t have any children. Then comes the confession.

A night spent sleeping on dirt and leaves is not how Claire Matchett expected to spend her vacation. She thought this would be a break. A week of hiking and hot tubs with two other couple friends. Then Claire’s minivan breaks down on a lonely dirt road. With no cell reception, the group has no choice but to hike the rest of the way to their hotel. But it turns out the woods aren’t as easy to navigate as they thought. Hours later, they are lost. Hopelessly lost. And as they navigate deeper into the woods, the members of their party are struck down mysteriously one by one.