Lubji Hoch escapes from the Nazis, moves to Berlin and changes his name to Richard Armitage. After a successful career in the British Army, he takes over a struggling newspaper and with unrivalled ruthlessness begins building his media empire. Meanwhile, Keith Townsend, the son of a millionaire and Oxford educated, returns to Australia from London to take over his father's newspaper with similar ambitions. As both men move their quest for power to the world stage, they realise they are more than a match for one another's brilliance and ambition.

William Warwick has always wanted to be a detective, and decides, much to his father’s dismay, that rather than become a lawyer like his father, Sir Julian Warwick QC, and his sister, Grace, he will join London’s Metropolitan Police Force. After graduating from university, William begins a career that will define his life: from his early months on the beat under the watchful eye of his first mentor, Constable Fred Yates, to his first high-stakes case as a fledgling detective in Scotland Yard’s arts and antiquities squad.

The epic tale of Harry Clifton's life begins in 1920, with the words "I was told that my father was killed in the war." A dock worker in Bristol, Harry never knew his father, but he learns about life on the docks from his uncle, who expects Harry to join him at the shipyard once he's left school. But then an unexpected gift wins him a scholarship to an exclusive boys' school, and his life will never be the same again. As he enters into adulthood, Harry finally learns how his father really died, but the awful truth only leads him to question, was he even his father?

Separated at birth by a desperate nurse who loses a millionaire's son to cot death, twin boys grow up without any knowledge of the other. Nat Cartwright lives with his middle-class birth parents and grows up to becomes a war hero in the Vietnam War before returning home to run for office in the Republican party. Fletcher Davenport becomes the only son of the millionaire couple. After graduating from Yale, he builds a reputation as a prolific criminal defence lawyer before he too delves into politics as a Democrat.

From strangers to rivals, four men embark on a journey for the highest stakes of all - the keys to No. 10 Downing Street. Unfolding over three decades, their honor will be tested, their loyalties betrayed, and their love of family and country challenged. But in a game where there is a first among equals, only one can triumph.