Like the men whose epic stories Jon Krakauer has told in his previous bestsellers, Pat Tillman was an irrepressible individualist and iconoclast. In May 2002, Tillman walked away from his $3.6 million NFL contract to enlist in the United States Army. He was deeply troubled by 9/11, and he felt a strong moral obligation to join the fight against al-Qaeda and the Taliban. Two years later, he died on a desolate hillside in southeastern Afghanistan.

In April 1992 a young man from a well-to-do family hitchhiked to Alaska and walked alone into the wilderness north of Mt. McKinley. His name was Christopher Johnson McCandless. He had given $25,000 in savings to charity, abandoned his car and most of his possessions, burned all the cash in his wallet, and invented a new life for himself.

In 1541, the brutal conquistador Gonzalo Pizarro and his well-born lieutenant Francisco Orellana set off from Quito in search of La Canela, South America's rumored Land of Cinnamon, and the fabled El Dorado, "the golden man". Driving an enormous retinue of mercenaries, enslaved natives, horses, hunting dogs, and other animals across the Andes, they watched their proud expedition begin to disintegrate even before they descended into the nightmarish jungle, following the course of a powerful river.

In August 1897, the young Belgian commandant Adrien de Gerlache set sail for a three-year expedition aboard the good ship Belgica with dreams of glory. His destination was the uncharted end of the earth: the icy continent of Antarctica. But de Gerlache’s plans to be first to the magnetic South Pole would swiftly go awry. After a series of costly setbacks, the commandant faced two bad options: turn back in defeat and spare his men the devastating Antarctic winter, or recklessly chase fame by sailing deeper into the freezing waters.

On October 12, 1972, a plane carrying a team of young rugby players crashed into the remote, snow-peaked Andes. Out of the 45 original passengers and crew, only 16 made it off the mountain alive. For 10 excruciating weeks, they suffered deprivations beyond imagining, confronting nature head-on at its most furious and inhospitable. And to survive, these men and women not only had to keep their faith; they had to make an impossible decision: Should they eat the flesh of their dead friends?