In the long awaited follow-up to the highly praised novel She's Come Undone, Dominick Birdsey must come to terms with himself, as well as with the schizophrenic twin brother he has spent his life both protecting and resenting.

When high-school teacher Caelum Quirk and his wife, Maureen, move to Littleton, Colorado, they both get jobs at Columbine High School. In April 1999, while Caelum is away, Maureen finds herself in the library at Columbine, cowering in a cabinet and expecting to be killed. Miraculously, she survives. But when Caelum and Maureen flee to an illusion of safety on the Quirk family's Connecticut farm, they discover that the effects of chaos are not easily put right.

After 27 years of marriage and three children, Anna Oh - wife, mother, outsider artist - has fallen in love with Viveca, the wealthy Manhattan art dealer who orchestrated her success. They plan to wed in the Oh family’s hometown of Three Rivers in Connecticut. But the wedding provokes some very mixed reactions and opens a Pandora’s Box of toxic secrets - dark and painful truths that have festered below the surface of the Ohs' lives.

Margaret Simon, almost 12, has just moved from New York City to the suburbs, and she’s anxious to fit in with her new friends. When she’s asked to join a secret club, she jumps at the chance. But when the girls start talking about boys, bras, and getting their first periods, Margaret starts to wonder if she’s normal. There are some things about growing up that are hard for her to talk about, even with her friends. Lucky for Margaret, she’s got someone else to confide in...someone who always listens.

In the summer of 1977, Victoria Leonard’s world changes forever when Caitlin Somers chooses her as a friend. Dazzling, reckless Caitlin welcomes Vix into the heart of her sprawling, eccentric family, opening doors to a world of unimaginable privilege, sweeping her away to vacations on Martha’s Vineyard, an enchanting place where the two friends become “summer sisters”. Now, years later, Vix is working in New York City. Caitlin is getting married on the Vineyard. And the early magic of their long complicated friendship has faded.