Patrick, or Gay Uncle Patrick (GUP, for short), has always loved his niece, Maisie, and nephew, Grant. That is, he loves spending time with them when they come out to Palm Springs for weeklong visits, or when he heads home to Connecticut for the holidays. But in terms of caretaking and relating to two children, no matter how adorable, Patrick is, honestly, overwhelmed. So when tragedy strikes and Maisie and Grant lose their mother and Patrick's brother has a health crisis of his own, Patrick finds himself suddenly taking on the role of primary guardian.

After Lucy is found wandering the streets, covered in her best friend Savvy’s blood, everyone thinks she is a murderer. Lucy and Savvy were the golden girls of their small Texas town: pretty, smart, and enviable. Lucy married a dream guy with a big ring and an even bigger new home. Savvy was the social butterfly loved by all, and if you believe the rumors, especially popular with the men in town. It’s been years since that horrible night, a night Lucy can’t remember anything about, and she has since moved to LA and started a new life.

After years of trying to make it as a writer in 1990s New York City, James Smale finally sells his novel to an editor at a major publishing house: none other than Jacqueline Kennedy Onassis. Jackie - or Mrs. Onassis, as she's known in the office - has fallen in love with James' candidly autobiographical novel, one that exposes his own dysfunctional family. But when the book's forthcoming publication threatens to unravel already fragile relationships, both within his family and with his partner, James finds that he can't bring himself to finish the manuscript.

A successful film professor and podcaster, Bodie Kane is content to forget her past—the family tragedy that marred her adolescence, her four largely miserable years at a New Hampshire boarding school, and the murder of her former roommate, Thalia Keith, in the spring of their senior year. Though the circumstances surrounding Thalia’s death and the conviction of the school’s athletic trainer, Omar Evans, are hotly debated online, Bodie prefers—needs—to let sleeping dogs lie.

One summer morning, twelve-year-old Edward Adler, his beloved older brother, his parents, and 183 other passengers board a flight in Newark headed for Los Angeles. Among them are a Wall Street wunderkind, a young woman coming to terms with an unexpected pregnancy, an injured veteran returning from Afghanistan, a business tycoon, and a free-spirited woman running away from her controlling husband. Halfway across the country, the plane crashes. Edward is the sole survivor.