Thirty-eight year old Cassandra is lost, alone, and grieving. Her much loved grandmother, Nell, has just died and Cassandra, her life already shaken by a tragic accident 10 years ago, feels like she has lost everything known and dear to her.

Living on her family’s gorgeous lakeside estate in Cornwall, England, Alice Edevane is a bright, clever, inquisitive, innocent, and precociously talented fourteen-year-old who loves to write stories. But the mysteries she pens are no match for the one her family is about to endure ...One midsummer’s eve, after a beautiful party drawing hundreds of guests to the estate has ended, the Edevanes discover that their youngest son, Theo, has vanished without a trace.

England, 1959: Laurel Nicolson is 16 years old, dreaming alone in her childhood tree house during a family celebration at their home, Green Acres Farm. She spies a stranger coming up the long road to the farm and then observes her mother, Dorothy, speaking to him. And then she witnesses a crime.

Alix St. Pierre. An unforgettable name for an unforgettable woman. She grew up surrounded by Hollywood glamor, but, as an orphan, never truly felt part of that world. In 1943, with WWII raging and men headed overseas to fight, she lands a publicity job to recruit women into the workforce. Her skills—persuasion, daring, quick-witted under pressure—catch the attention of the U.S. government and she finds herself with an even bigger assignment: sent to Switzerland as a spy. Soon Alix is on the precipice of something big, very big. But how far can she trust her German informant…?

They’re one of the country’s most telegenic couples: beloved TV journalist Sara Lowell and New York’s hottest basketball star, Michael Silverman. Their family and social connections tie them to the highest echelons of the political, medical, and sports worlds - threads that will tangle them up in one of the most controversial and deadly issues of our time. In a clinic on Manhattan’s Upper West Side, a doctor has dedicated his life to eradicating a divisive and devastating disease. One by one, his patients are getting well.