Everyone in the small town of Denton is searching for Isabelle Coleman, a missing 17-year-old girl. All they've found so far is her phone and another girl they didn't even know was missing. Mute and completely unresponsive to the world around her, it's clear this mysterious girl has been damaged beyond repair. All Detective Josie Quinn can get from her is a name: Ramona. Currently suspended from the force for misconduct, Josie takes matters into her own hands as the name leads her to evidence linking the two girls.

In the remote forests of Stillwater, Minnesota, you can scream for days and no one will hear you. So when the bodies of two 15-year-old girls are discovered frozen in the snow, Special Agent Nikki Hunt is sure the killer is local: Someone knew where to hide the girls and thought they would never be found. Though Nikki hasn’t been home in 20 years, she knows she must take over the case.

Thirteen years ago, Assemblyman Derrick Bell was murdered in his home by an intruder. His wife, Noelle Marshall, was left for dead. The crime was unsolved, but it wasn’t forgotten. Today the FBI is tackling a fresh perspective on the case and looking to Noelle, now a detective for the Deschutes County sheriff’s office, for new clues. It is reopening everything Noelle thought was behind her. Memories of her escape from a traumatic childhood. A marriage that wasn’t the perfect love story she’d been promised. And a husband whose charm and privilege hid a dark side.

The beautiful young woman is perfectly still, curled up in the trunk of the car, her long dark hair hiding her face. Her cotton blouse has ridden up a little, revealing two small dots an inch apart on her back. Just like the others. Guilt has kept FBI Agent Tori Hunter away from her home in Manchester Bay, Minnesota for 20 years, ever since her twin sister disappeared on the Fourth of July, when the girls should have been together. But when she receives an anonymous newspaper clipping about another missing girl, Genevieve, Tori is dragged back to the past.

It’s been five years since Detective Amanda Steele’s life was derailed by the tragic death of her young daughter. The small community of Dumfries, Virginia, may have moved on, but Amanda cannot. When the man who killed Lindsey is found murdered, she can’t keep away from the case.

Fourteen years ago, Kaitlin Roe was the lone witness to the abduction of her cousin Gina. She still remembers that lonely Virginia road. She can still see the masked stranger and hear Gina’s screams. And she still suffers the guilt of running away in fear and resents being interrogated as a suspect in the immediate aftermath. Now Kaitlin has only one way to assuage the pain and nightmares—by interviewing everyone associated with the unsolved crime for a podcast that could finally bring closure to a case gone cold.

FBI analyst Kassidy Bishop is assigned to the "'For You' Killer" task force after a series of sadistic murders bearing the same signature arise in different parts of the country. The homicides are both calculated and savage, occurring in different states, but bearing the same signature: the words "for you" scribbled at each crime scene. The case chills Kassidy, bringing back memories of her own encounter with a violent criminal five years earlier.

FBI special agent Mercy Kilpatrick has been waiting her whole life for disaster to strike. A prepper since childhood, Mercy grew up living off the land — and off the grid — in rural Eagle’s Nest, Oregon. Until a shocking tragedy tore her family apart and forced her to leave home. Now a predator known as the cave man is targeting the survivalists in her hometown, murdering them in their homes, stealing huge numbers of weapons, and creating federal suspicion of a possible domestic terrorism event.

Eleven years ago, the Co-ed Slayer murdered nine female students on the Oregon State University campus. Lacey Campbell barely escaped his attack, but lost her best friend whose remains were never found. As the sole surviving victim, Lacey helped send the sadistic serial killer to prison for life. Now a forensic odontologist examining teeth and bones for the state Medical Examiner, Lacey is devastated when she arrives at a crime scene and identifies the skeletal remains as her college friend’s.

Special Agent Macy Crow is a survivor. After a vicious hit-and-run nearly kills her, she gets right back to work, and now she’s gunning for a spot on the FBI’s elite profiling team. As an audition, she offers to investigate the recently discovered bones of Tobi Turner, a high school girl who disappeared fifteen years ago. While investigating with local sheriff Mike Nevada, a former colleague and onetime lover, Macy discovers a link between Tobi’s case and several others that occurred around the same time as her disappearance.