The year was 1917. As a war raged across the world, young American women flocked to work, painting watches, clocks, and military dials with a special luminous substance made from radium. It was a fun job, lucrative and glamorous - the girls themselves shone brightly in the dark, covered head to toe in the dust from the paint. They were the radium girls. As the years passed, the women began to suffer from mysterious and crippling illnesses.

What won't we try in our quest for perfect health, beauty, and the fountain of youth? Well, just imagine a time when doctors prescribed morphine for crying infants. When liquefied gold was touted as immortality in a glass. And when strychnine - yes, that strychnine, the one used in rat poison - was dosed like Viagra. Looking back with fascination, horror, and not a little dash of dark, knowing humor, Quackery recounts the lively, at times unbelievable, history of medical misfires and malpractices.

Every Tudor Queen had ladies-in-waiting. They were her confidantes and her chaperones. Only the Queen's ladies had the right to enter her most private chambers, spending hours helping her to get dressed and undressed, caring for her clothes and jewels, listening to her secrets. But they also held a unique power. A quiet word behind the scenes, an appropriately timed gift, a well-negotiated marriage alliance were all forms of political agency wielded expertly by women.

Over the last two decades, there has been an inescapable rise of anger and aggression across our planet. Hate speech has become increasingly prevalent online, Western governments are turning towards authoritarianism and populism, and extremist groups are rising across both the left and the right ends of the political spectrum. Every day, it seems, we're hearing more angry voices and fearful opinions, we're seeing more threats and frightening news, and we're reacting faster and less rationally.

Follow a journalist and TV producer from 48 Hours and 60 Minutes as she carves out a career in the ruthless, knives-out world of true crime television . . . one killer story at a time.