Evan Smoak is a man with skills, resources, and a personal mission to help those with nowhere else to turn. He’s also a man with a dangerous past. Chosen as a child, he was raised and trained as an Orphan, an off-the-books black box program designed to create the perfect deniable intelligence asset: An assassin. Evan was Orphan X - until he broke with the program and used everything he learned to disappear. But now someone is on his tail.

Joey Morales was the last recruit of the government's full black operation, the Orphan Program. Trained to be an assassin until she washed out, she was rescued by Evan Smoak, the former agent known as Orphan X. Now Joey, a world-class hacker, starts training for one of her biggest challenges yet: having a normal life. Still a teenager, she discovers she loves music as much as hacking, if not more so. But as she carves out a space for herself, the one thing missing is a family to support her endeavors.

Nate Overbay, a former soldier suffering from PTSD and ALS, goes to an 11th-floor bank and climbs out the bathroom window onto the ledge, ready to end it all. But as he’s steeling himself to jump, a crew of gunmen bursts into the bank and begins viciously shooting employees and customers. With nothing to lose, Nate climbs back inside, confronts the robbers, and with his military training, starts taking them out, one by one. The last man standing leaves Nate with a cryptic warning: “He will make you pay in ways you can’t imagine.” Soon enough, Nate learns what this means.

Tim Rackley, a deputy U.S. marshal, watches helplessly as his daughter's killer walks free on a legal technicality. He is suddenly forced to explore his own deadly options, a quest that leads him into the welcoming fold of "The Commission".

Court Gentry is known as The Gray Man—a legend in the covert realm, moving silently from job to job, accomplishing the impossible, and then fading away. And he always hits his target. But there are forces more lethal than Gentry in the world. And in their eyes, Gentry has just outlived his usefulness. Now, he is going to prove that for him, there's no gray area between killing for a living-and killing to stay alive.