In 1960, free-spirited Doreen is a recent high-school grad and waitress in a Chicago diner. She doesn't know Margie, 16 and bookish, who lives a sheltered suburban life, but they soon meet when unplanned pregnancies send them to the Holy Family Home for the Wayward in rural Illinois. Assigned as roommates because their due dates line up, Margie and Doreen navigate Holy Family's culture of secrecy and shame and become fast friends as the weight of their coming decision - to keep or surrender their babies - becomes clear.

Except, they soon realize, the decision has already been made for them. Holy Family, like many of the maternity homes where 1.5 million women "relinquished" their babies in what is now known as the Baby Scoop Era, is not interested in what the birth mothers want. In its zeal to make the babies "legitimate" in closed adoptions, Holy Family manipulates and bullies birth mothers, often coercing them to sign away their parental rights while still under the effects of anesthesia.

What happens next, as their babies are born and they leave Holy Family behind, will force each woman to confront the depths and limits of motherhood and friendship, and fight to reclaim control over their own lives.