William Lowell Kane and Abel Rosnovski, one the son of a Boston millionaire, the other a penniless polish immigrant-born on the same day near the turn of the century on opposite sides of the world-are brought together by fate and the quest of a dream. Two men - ambitious, powerful, ruthless - are locked in a relentless struggle to build an empire, fueled by their all-consuming hatred.

The epic tale of Harry Clifton's life begins in 1920, with the words "I was told that my father was killed in the war." A dock worker in Bristol, Harry never knew his father, but he learns about life on the docks from his uncle, who expects Harry to join him at the shipyard once he's left school. But then an unexpected gift wins him a scholarship to an exclusive boys' school, and his life will never be the same again. As he enters into adulthood, Harry finally learns how his father really died, but the awful truth only leads him to question, was he even his father?

When Charlie Trumper inherits the barrow his grandfather used to peddle fruit and vegetables in turn-of-the-century Whitechapel, England, he inherits his enterprising spirit as well. Charlie's deeply held ambition to raise himself out of the poverty of London's East End is destined to be realized, but there are many obstacles to overcome, including a tour of duty at the front in World War I, where he encounters the man who will become his lifelong enemy.

William Warwick has always wanted to be a detective, and decides, much to his father’s dismay, that rather than become a lawyer like his father, Sir Julian Warwick QC, and his sister, Grace, he will join London’s Metropolitan Police Force. After graduating from university, William begins a career that will define his life: from his early months on the beat under the watchful eye of his first mentor, Constable Fred Yates, to his first high-stakes case as a fledgling detective in Scotland Yard’s arts and antiquities squad.

Separated at birth by a desperate nurse who loses a millionaire's son to cot death, twin boys grow up without any knowledge of the other. Nat Cartwright lives with his middle-class birth parents and grows up to becomes a war hero in the Vietnam War before returning home to run for office in the Republican party. Fletcher Davenport becomes the only son of the millionaire couple. After graduating from Yale, he builds a reputation as a prolific criminal defence lawyer before he too delves into politics as a Democrat.