In the dead of winter, handwriting expert Claudia Rose journeys to Maine to retrieve a manuscript about convicted female serial killer, Roxanne Becker. The manuscript, written by Professor Madeleine Maynard, who was, herself, brutally murdered, exposes a shocking secret: explosive research about a group of mentally unstable grad students selected for a special project and dubbed “Maynard’s Maniacs”. Was Madeleine conducting research that was at best, unprofessional - and at worst, downright harmful and potentially dangerous? Could that unorthodox research have turned deadly? 

Claudia finds herself swept up in the mystery of Madeleine’s life - and death. But Claudia soon realizes that Madeleine left behind more questions than answers, and no shortage of suspects. The professor’s personal life yields a number of persons who might have wanted her dead, and her academic success and personal fortune clearly made her the envy of fellow faculty members.

The university anticipates being the beneficiary of Madeline’s estate but that seems in question when a charming stranger, claiming to be Madeleine’s nephew, turns up brandishing a new will. The local police chief prevails upon Claudia to travel into town to examine the newly produced, handwritten will. Rushing back to Madeleine’s isolated house to escape an impending storm, Claudia becomes trapped in a blizzard. With a killer.