Lying on the cold metal table, Voyne Ray Cox knew the drill. This was his ninth round of cancer treatment - which is why he was certain that what happened next couldn't be right. He heard a sizzling sound and saw a blue flash. And then - agony. It was like someone had thrust a hot skewer through his shoulder. He cried out in pain, but the operator was down the corridor and she couldn't hear him. She blasted him again and again with the red-hot radiation beam.

Ray wasn't the first patient to be burned by the Therac-25 therapy machine, and he wouldn't be the last. Its dual-purpose design, controlled by a software programme, was supposed to offer hospitals more bang for their buck. But as patient after patient suffered ulcerated skin and yawning lesions, it should have been clear that something was horribly wrong. Why did it take so long for anyone to put this awful puzzle together?

For a full list of sources, see the show notes at timharford.com.

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Acclaimed author Michael Lewis discusses his time with Sam Bankman-Fried and why he thinks both high finance and Effective Altruism shaped the 'Crypto King's' worldview, ultimately landing him in jail. Plus, we hear about the people fighting terrorism, cave-ins and brain-eating amoeba from Michael's new book 'Who Is Government?'.

For a full list of sources, see the show notes at timharford.com.

Get ad-free episodes, plus an exclusive monthly bonus episode, to Cautionary Tales by subscribing to Pushkin+ on Apple Podcasts or Pushkin.fm. Pushkin+ subscribers can access ad-free episodes, full audiobooks exclusive binges, and bonus content for all Pushkin shows.

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A radical thought experiment transforms the lives of a new breed of philanthropists, as they follow the logic of altruism to extraordinary lengths. The most famous convert to the Effective Altruism movement, Sam Bankman-Fried, is either a humanitarian hero, a con artist at an astonishing scale, or most bafflingly, both.

For a full list of sources, see the show notes at timharford.com.

Get ad-free episodes, plus an exclusive monthly bonus episode, to Cautionary Tales by subscribing to Pushkin+ on Apple Podcasts or Pushkin.fm. Pushkin+ subscribers can access ad-free episodes, full audiobooks exclusive binges, and bonus content for all Pushkin shows.

Subscribe on Apple: apple.co/pushkin
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See omnystudio.com/listener for privacy information.