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This Week in Virology

This Week in Virology

Auteur(s): Vincent Racaniello
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TWiV is a podcast about viruses - the kind that make you sick.Vincent Racaniello 2022 Nature et écologie Science Sciences biologiques
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  • TWiV 1277: Vaccine talk with Jake Scott
    Dec 7 2025

    Infectious diseases physician Jake Scott returns to TWiV to discuss the dangerous anti-vaccine policies being established in the US and what RFK Jr. and his associates get wrong.

    Hosts: Vincent Racaniello, Rich Condit, and Angela Mingarelli

    Guest: Jake Scott

    Subscribe (free): Apple Podcasts, RSS, email

    Become a patron of TWiV!

    Links for this episode
    • Support science education at MicrobeTV
    • Vaccine RCT spreadsheet (CIDRAP)
    • What RFK Jr gets wrong about vaccines (Conversation)
    • RFK Jr's case against mRNA vaccines collapses (STAT)
    • Too many kids' vaccines? Think again (STAT)
    • Timestamps by Jolene Ramsey. Thanks!
    Weekly Picks

    Angela – Angela Palmer, science meets art (one, two)
    Rich – TWiV Special: A Shot of Hep B with Thomas Tu; TWiV Special: A shot of HepB with Chari Cohen
    Vincent – TSA is checking senior's phones for these 5 apps

    Intro music is by Ronald Jenkees

    Send your virology questions and comments to twiv@microbe.tv

    Content in this podcast should not be construed as medical advice.

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    1 h et 39 min
  • TWiV 1276: Clinical update with Dr. Daniel Griffin
    Dec 6 2025
    In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss the positive side effect of the shingles vaccine on dementia outcomes and how one dose of the HPV vaccine is non-inferior to two doses, but are dismayed about the FDA's secrecy around the inflammatory statement that the COVID-19 vaccine is linked to the death of 10 children. Dr. Griffin then deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, effectiveness of maternal administration of the RVS vaccine or the COVID vaccine for neonates, where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, how celiac plexus blocks improves gastrointestinal long COVID symptoms, brain alterations and neurodegenerative processes in long COVID cognitive impairment and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode The effect of shingles vaccination at different stages of the dementia disease course(Cell)FDA links 10 children's deaths to COVID-19 vaccines. Doctors want proof (ABC News)Subject: Deaths in children due to COVID-19 vaccines and CBER's path forward Dear Team CBER,(Washington Post)Noninferiority of One HPV Vaccine Dose to Two Doses(NEJM)Marburg Outbreak in Ethiopia: Current Situation (CDC: Marburg Virus Disease)Washington state resident believed to be the first to die from a rare strain of bird flu (AP News) Wastewater for measles (WasterWater Scan)Measles cases and outbreaks (CDC Rubeola)Tracking Measles Cases in the U.S. (Johns Hopkins)Measles vaccine recommendations from NYP (jpg)Weekly measles and rubella monitoring (Government of Canada)Measles (WHO)Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola))Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Measles (CDC Measles (Rubeola))Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America)Deaths following vaccination: what does the evidence show (Vaccine)Influenza: Waste water scan for 11 pathogens (WastewaterSCan)US respiratory virus activity (CDC Respiratory Illnesses)Respiratory virus activity levels (CDC Respiratory Illnesses)Weekly surveillance report: cliff notes (CDC FluView)ACIP Recommendations Summary (CDC: Influenza)Types of Influenza Viruses (CDC: Influenza (flu))Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season(FDA)RSV: Waste water scan for 11 pathogens (WastewaterSCan) Respiratory Diseases (Yale School of Public Health)US respiratory virus activity (CDC Respiratory Illnesses)RSV-Network (CDC Respiratory Syncytial virus Infection)Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Maternal and Neonatal Outcomes After Respiratory Syncytial Virus Prefusion F Protein Vaccination During Pregnancy (Obstetrics & Gynecology)Waste water scan for 11 pathogens (WastewaterSCan)COVID-19 deaths (CDC)Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)COVID-19 national and regional trends (CDC)COVID-19 variant tracker (CDC)SARS-CoV-2 genomes galore (Nextstrain)Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV)Effectiveness of COVID-19 vaccines against post-COVID-19 condition/long COVID: systematic review and meta-analysis (CMI: Clinical Microbiology and Infection)SARS-CoV-2Infection Versus Vaccination During Pregnancy: Implications for Placental Antibody Transfer (The Pediatric Infectious Disease Journal)Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC)NIH COVID-19 treatment guidelines (NIH)Drug interaction checker (University of Liverpool)Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro)Understanding Coverage Options (PAXCESS) Infectious Disease Society guidelines for treatment and management (ID Society)Molnupiravir safety and efficacy (JMV)Convalescent plasma recommendation for immunocompromised (ID Society)What to do when sick with a respiratory virus (CDC)Managing healthcare staffing shortages (CDC) Anticoagulation guidelines (hematology.org)Daniel Griffin's evidence based medical practices for long COVID (OFID)Long COVID hotline (Columbia : Columbia University Irving Medical Center)The answers: Long COVIDCase Report: Celiac plexus block improves ...
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    55 min
  • TWiV 1275: An amazing sequence and a gutsy therapy
    Nov 30 2025

    TWiV explains the Nobel Prize-winning discovery of pre-mRNA splicing, and engineering bacteriophage to deliver proteins to the human intestine.

    Hosts: Vincent Racaniello, Kathy Spindler, and Brianne Barker

    Subscribe (free): Apple Podcasts, RSS, email

    Become a patron of TWiV!

    Links for this episode
    • Support science education at MicrobeTV
    • Immune 100 live at the Incubator
    • Spliced segments of adenovirus mRNA (PNAS)
    • An amazing sequence in adenovirus mRNA (Cell)
    • Nobel Prize for mRNA splicing (Nobel)
    • A predominant undecanucleotide in adenovirus late mRNAs (Cell)
    • Splicing RNA with Phillip A. Sharp (ASM)
    • Protein production in the gut by engineered phage (Nat Biotech)
    • Engineered phage T4 (Curr Op Virol)
    • Timestamps by Jolene Ramsey. Thanks!
    Weekly Picks

    Brianne – Can You Identify These Lines from Classic SciFi Novels?
    Kathy – Saturday Morning Physics, Photograph 51 and JCE article
    Rich – Wikipedia:Wiki Science Competition 2025 in the United States
    Jolene – Data visualization workshop
    Vincent – Transformer: The Deep Chemistry of Life and Death by Nick Lane

    Intro music is by Ronald Jenkees

    Send your virology questions and comments to twiv@microbe.tv

    Content in this podcast should not be construed as medical advice.

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    1 h et 49 min
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