Today we’re sharing an episode from American Optimist featuring Marc Andreessen in conversation with Joe Lonsdale, recorded live at the inaugural Ronald Reagan Economic Forum.

They explore one of the most urgent and complex questions of our time: Can AI and robotics catalyze a new era of American industrial strength—and how do we ensure the entire country, including rural communities, shares in the upside?

Marc walks through the history of U.S. industrialization, the lessons of tariffs and trade from leaders like McKinley, and how America’s shift to a services-based economy helped fuel our current urban-rural divide. The conversation spans immigration policy, housing, education, energy, and the path to a true AI-powered manufacturing revival—touching on what needs to change and how.

This episode is a must-listen for anyone thinking about the future of American productivity, growth, and leadership in the age of AI.

Resources:

Find Marc on X: https://x.com/pmarca

Follow Joe on X: https://x.com/jtlonsdale

You can find his writings here: https://blog.joelonsdale.com/

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

U.S. per capita energy usage peaked in 1973. Since then? Flat. Meanwhile, China’s per capita energy use has grown 9x.

Today, AI, EVs, manufacturing, and data centers are driving demand for more electricity than ever—and our grid can’t keep up.

In this episode, a16z general partners David Ulevitch and Erin Price-Wright, along with investing partner Ryan McEntush from the American Dynamism team, join us to unpack:

– How America’s grid fell behind

– Why we "forgot how to build" power infrastructure

– The role of batteries, solar, nuclear, and software in reshaping the grid

– How AI is both stressing and helping the system

– What it’ll take to build a more resilient, decentralized, and dynamic energy future

Whether you’re a founder, policymaker, or just someone who wants their lights to stay on, this conversation covers what’s broken—and how to fix it.

Resources:

Find David on X: https://x.com/davidu

Find Erin on X: https://x.com/espricewright

Find Ryan on X: https://x.com/rmcentush

Timestamps:

00:00 Introduction

01:05 Challenges and Solutions for Modernizing the Grid

01:56 Decentralized Energy and Technological Innovations

02:34 Grid Capacity and Transformer Issues

04:10 The Role of AI and Software in Energy Management

04:55 Policy and Workforce Challenges

08:44 Texas vs. New York: A Tale of Two Grids

10:31 The Importance of Battery Technology

13:11 Balancing Energy Sources: Solar, Nuclear, and More

14:54 The Future of Energy Consumption and Grid Management

19:45 Wind Power: The Forgotten Energy Source

20:53 Challenges in Grid Monitoring and Communication

22:19 Load Forecasting and Weather Impact

23:49 Nuclear Energy: Current State and Future Prospects

26:44 Small Modular Reactors and Micro Reactors

30:55 Technological Innovations in Grid Management

35:41 The Role of AI in Regulatory Processes

41:39 National Security and the Electrical Grid

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Find a16z on LinkedIn: https://www.linkedin.com/company/a16z

Subscribe on your favorite podcast app: https://a16z.simplecast.com/

Follow our host: https://x.com/eriktorenberg

Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

In this episode, a16z General Partner Martin Casado sits down with Box cofounder and CEO Aaron Levie to talk about how AI is changing not just software, but the structure and speed of work itself.

They unpack how enterprise adoption of AI is different from the consumer wave, why incumbents may be better positioned than people think, and how the role of the individual contributor is already shifting from executor to orchestrator. From vibe coding and agent UX to why startups should still go vertical, this is a candid, strategic conversation about what it actually looks like to build and operate in an AI-native enterprise.

Aaron also shares how Box is using AI internally today, and what might happen when agents outnumber employees.

Resources:

Find Aaron on X: https://x.com/levie

Find Martin on X: https://x.com/martin_casado

Stay Updated:

Let us know what you think: https://ratethispodcast.com/a16z

Find a16z on Twitter: https://twitter.com/a16z

Find a16z on LinkedIn: https://www.linkedin.com/company/a16z

Subscribe on your favorite podcast app: https://a16z.simplecast.com/

Follow our host: https://x.com/eriktorenberg

Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.