Cardiovascular-Kidney-Metabolic (CKM) Syndrome leads to poor health outcomes, and is affecting individuals at younger and younger ages. The PREVENT calculator helps identify individuals earlier in the disease progression, allowing time for intervientions that may lead to a regression on the stages of CKM. Guest Chiadi Ndumele, MD, PhD. also describes shared decision-making, and value- and volume-based care models.

PREVENT calculator: https://professional.heart.org/en/guidelines-and-statements/prevent-calculator

Pooled 10-year ASCVD Risk Calculator: https://tools.acc.org/ascvd-risk-estimator-plus/#!/calculate/estimate/

2025 Hypertension Guidelines Update: https://www.heart.org/en/health-topics/high-blood-pressure/the-facts-about-high-blood-pressure/high-bp-top-10

AHA CKM Scientific Statement: https://professional.heart.org/en/science-news/cardiovascular-kidney-metabolic-health-a-presidential-advisory

PCNA CKM Resource list: https://pcna.net/resources/patient-education/patient-information/cardiovascular-kidney-metabolic-syndrome-resources/

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Afib is on the rise with significant effects on morbidity and mortality. The stagnation of blood in the left atrium and left atrial appendage (LAA) places patients at risk for thromboembolism and stroke. By ligating or closing off the LAA, the risk can be significantly reduced. This intervention offers a valuable alternative to medication, improving safety and quality of life for patients through a minimally invasive, durable stroke prevention strategy. Learn more about the procedure and steps for referring your eligible patient.

https://chads2vasccalculator.com/

https://www.watchman.com/en-us-hcp/oac-alternative.html?utm_source=oth_site&utm_medium=display-direct&utm_campaign=ic-wm-us-dtr-hcp_app&utm_content=pcna_podcast_oac_alternative-n-n-n&cid=dsp10020937

https://www.watchman.com/en-us-hcp/patient-selection-referrals/patient-pre-screening-tool.html?utm_source=oth_site&utm_medium=display-direct&utm_campaign=ic-wm-us-dtr-hcp_app&utm_content=pcna_podcast_patient_screener-n-n-n&cid=dsp10020938

https://pcna.net/resource/afib-prepare-for-your-next-visit-discussion-guide/

https://pcna.net/resource/the-beat-goes-on-living-with-atrial-fibrillation-online-interactive-patient-guide/

https://pcna.net/resource/afib-and-stroke-infographic/

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Afib is on the rise with significant effects on morbidity and mortality. Afib is a progressive disease with various treatment methods to match to your patients' risk factors and health goals. Stroke prevention is a crucial risk factor to evaluate on the progressive journey of a patient experiencing Afib. Learn more about the assessment and identification of patients with Afib at risk for stroke and next steps in prevention.

https://www.ahajournals.org/doi/10.1161/CIR.0000000000001193

https://chads2vasccalculator.com/

https://www.uptodate.com/contents/image?imageKey=HEME%2F75259

https://pcna.net/resource/afib-prepare-for-your-next-visit-discussion-guide/

https://pcna.net/resource/the-beat-goes-on-living-with-atrial-fibrillation-online-interactive-patient-guide/

https://pcna.net/resource/afib-and-stroke-infographic/

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Connection can be the key to health, and those facing disconnection are at significantly higher risk of CVD, stroke, T2D, and other health issues. Guest Lora Peppard, PhD, DNP, PMHNP-BC, describes the importance of relationships and the 6 core beliefs that can help our patients and ourselves have improved health.

Resources:

Related PCNA CE course: https://pcna.net/course/the-extraordinary-impact-of-connection-on-mental-and-cardiovascular-health/

Our Epidemic of Loneliness and Isolation: https://www.hhs.gov/sites/default/files/surgeon-general-social-connection-advisory.pdf

https://www.julianneholtlunstad.com/

https://bronnieware.com/regrets-of-the-dying/

https://www.zachmercurio.com/

https://publichealth.jhu.edu/faculty/3038/christina-d-bethell

Family Resilience Connection Index: https://nurtureconnection.org/child-flourishing-a-critical-indicator-for-erh/

American Psychiatric Nurses Association https://www.apna.org/

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* Add FAAN to Anita's creds after Oct. 18.

Guests: Anita Rich, DNP, RN, CHFN, CDCES, FAAN, and Jane DeMeis.

Related resources:

PCNA CKM tools and resources: https://pcna.net/resources/patient-education/patient-information/cardiovascular-kidney-metabolic-syndrome-resources/

2025 ACC Expert Consensus Statement on Medical Weight Mgmt for Optimization of CV Health: https://www.jacc.org/doi/10.1016/j.jacc.2025.05.024

Adiponectin, Leptin and CV Disorders: (https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.120.314458

Racial and Ethnic Disparities in Adult Obesity in the US: https://www.cdc.gov/pcd/issues/2019/18_0579.htm

Cardiometabolic Syndrome: A Global Health Issue: https://www.uspharmacist.com/article/cardiometabolic-syndrome-a-global-health-issue

Taking Aim At Belly Fat: https://www.health.harvard.edu/newsletter_article/taking-aim-at-belly-fat

Gender Disparities in People Living with Obesity: https://pubmed.ncbi.nlm.nih.gov/34526743/

Systematic review and meta-analysis suggests obesity predicts onset of CKD: https://www.sciencedirect.com/science/article/pii/S0085253816307529

AHA Weight-Loss Strategies for Prevention and Treatment of Hypertension: https://pubmed.ncbi.nlm.nih.gov/34538096/

Renal Fat Accumulation Assessed by MRI or CT and Metabolic Disorders: https://pmc.ncbi.nlm.nih.gov/articles/PMC12194363/

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The bidiretional relationship between cardiac and renal systems means that any dysfunction can cause a cascade of health issues. Learn about team-based care strategies for nurses and other professionals to monitor and manage patients with these conditions from guests Andrew Bzowyckyj, PharmD, BCPS, CDCES, FAPhA, FADCES, and Serina Gbaba, DNP, MBA, FNP-BC.

PCNA CKM tools and resources: https://pcna.net/resources/patient-education/patient-information/cardiovascular-kidney-metabolic-syndrome-resources/

IPEC core competencies (Interprofessional Education Collaborative): https://www.ipecollaborative.org/ipec-core-competencies

CVD in CKD: Pathophysiological Insights and Therapeutic Options: https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.120.050686

Social Determinants of CVD:https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.121.319811

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Cardiovascular-kidney-metabolic (CKM) syndrome is progressive, but can be halted or even reversed with effective management. Guests Chiai Ndumele, MD, PhD, and Joe Saseen, PharmD, BCPS, BCACP, describe the role of inflammation and how the biologic factors for diagnosis and treatment are nested within a patient's social context.

2023 AHA Statement Cardiovascular-Kidney-Metabolic Health: https://www.ahajournals.org/doi/10.1161/cir.0000000000001184

Related Resources:

PCNA CKM tools and resources: https://pcna.net/resources/patient-education/patient-information/cardiovascular-kidney-metabolic-syndrome-resources/

AHA Cardiovascular Kidney Metabolic Health Presidential Advisory: https://professional.heart.org/en/science-news/cardiovascular-kidney-metabolic-health-a-presidential-advisory

AHA CKM Syndrome Implementation Guide: https://www.heart.org/en/professional/cardiovascular-kidney-metabolic-health/implementation

PCNA CKM Resource list: https://pcna.net/resources/patient-education/patient-information/cardiovascular-kidney-metabolic-syndrome-resources/

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