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Inside Precision Medicine Podcasts

Inside Precision Medicine Podcasts

Auteur(s): Kathryn Ryan
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À propos de cet audio

Hosted by Damian Doherty, Editor in Chief of Inside Precision Medicine, Inside Precision Medicine Podcasts bring you the latest conversation, insight, and education from the world of precision medicine.

Hosted on Acast. See acast.com/privacy for more information.

Kathryn Ryan
Science Sciences biologiques
Épisodes
  • Epigenetics in the Multi-Omic Era: Predicting Alzheimer’s Before It Starts
    Dec 15 2025

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    45 min
  • Transforming Breast Cancer Screening: Lessons from a Landmark Colombian Study
    Dec 4 2025

    This podcast features George Busby discussing his work on polygenic risk scores (PRS) and their expanding role in precision medicine. He reflects on how he became interested in PRS, recent advances in methylation risk scores (MRS), and the potential of integrating PRS and MRS to improve disease prediction. The conversation highlights his breast cancer study in Colombian women, exploring its hypothesis, findings, and global relevance. Busby also addresses challenges in translating genomic research into clinical practice, efforts to enhance predictive models, and how technological evolution continues to drive innovation and future directions in genomic medicine.



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    51 min
  • Methylation Matters
    Nov 10 2025
    This Inside Precision Medicine podcast explores how advances in DNA methylation research are transforming diabetes care. The discussion with Charlotte Ling covers motivations for focusing on methylation as valuable prognosticator of disease, the advantages of methylation risk scores (MRS) compared to polygenic risk scores (PRS), and novel gene associations linked to cardiovascular complications in diabetes. She articulates the validation needs across diverse populations, the influence of lifestyle on methylation stability, and strategies for translating these biomarkers into clinical tools. Finally, she reflects on evolving technologies, future applications of methylation biomarkers, and the potential for precision diagnostics and targeted interventions in high-risk diabetic patients.

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    43 min
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