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Edinburgh, 1847. Will Raven is a medical student, apprenticing for the brilliant and renowned Dr Simpson. Sarah Fisher is Simpson’s housemaid and has all of Raven’s intelligence, but none of his privileges. As bodies begin to appear across the Old Town, Raven and Sarah find themselves propelled headlong into the darkest shadows of Edinburgh’s underworld. And if either of them are to make it out alive, they will have to work together to find out who’s responsible for the gruesome deaths.

Edinburgh, 1854, and a killer stalks the streets. Body parts have been found across the city—a foot in the Surgeon's Hall, another beneath a debtor's floorboards, more pieces in the soil of a freshly filled grave—and Will Raven, assistant to the great Dr Simpson, is being asked questions about the crime. His day job is demanding enough, striving to make his name as an obstetrician, and his home life with a second child on the way is exhausting. But Will usually finds the company of his colleague Sarah Fisher, a young widow and fellow-trainee, reviving.

Edinburgh, 1853. Mesmerism is seeing a revival across the city. While most scientists avoid engaging with such quackery, the respected Dr Simpson has kept an open mind, testing hypnosis on his patients. But when Cora Carlton, socialite and wife of a wealthy entrepreneur, is mysteriously found dead in her home, whispers turn to rumours and rumours turn to fact, with all fingers pointing to her Doctor, Simpson. Desperate to clear their mentor's name, Dr Will Raven and Sarah Fisher join forces to find the truth about Cora's death.

Apprentice Sarah Fisher is helping to fund Dr Will Raven's emerging medical practice in exchange for being secretly trained as a medic, should the rules barring women ever change. Sarah needs no instruction in the inequalities that beset her gender, but even she has her eyes opened to a darker reality when a relative seeks her help in searching for her missing daughter. Annabel Banks was promised a situation in a prestigious household, but there has been no word from her since she left home, and the agency that arranged her position says she never appeared.

Cal may only be twelve years old, but his father has threatened to throw him onto the streets if he doesn’t start earning his keep. Keen to prove himself, he unearths an opportunity through stealthy eavesdropping. Two gentlemen need help transporting an unnamed cargo across the Firth of Forth, no questions asked. Cal is happy to secure the job, but soon discovers that holding up his end will entangle him in a ruthless underworld of thievery, smuggling and body snatchers.

Edinburgh, 1849. Hordes of patients are dying all across the city, with doctors finding their remedies powerless. And a whispering campaign seeks to paint Dr. James Simpson, pioneer of medical chloroform, as a murderer. Determined to clear Simpson’s name, his protégé Will Raven and former housemaid Sarah Fisher must plunge into Edinburgh’s deadliest streets and find out who or what is behind the deaths. Soon they discover that the cause of the deaths has evaded detection purely because it is so unthinkable.

Dr. Will Raven is a man seldom shocked by human remains, but even he is disturbed by the contents of a package washed up at the Port of Leith. Stranger still, a man Raven has long detested is pleading for his help to escape the hangman. Back in the townhouse of Dr. James Simpson, Sarah Fisher has set her sights on learning to practice medicine. Almost everyone seems intent on dissuading her from this ambition, but when word reaches her that a woman has recently obtained a medical degree despite her gender, Sarah decides to seek her out.

Mord und Medizin im historischen Edinburgh. Edinburgh, 1850. Obwohl die Stadt an der Spitze der modernen Medizin steht, scheinen die Heilmittel der Ärzte wirkungslos. Überall sterben Menschen. Selbst dem geschätzten Dr. James Simpson wird die Schuld für den fragwürdigen Tod eines seiner Patienten zugeschoben. Sein Schützling Will Raven und das ehemalige Hausmädchen Sarah Fisher sind entschlossen, Simpsons Namen reinzuwaschen.

1847: Eine brutale Mordserie an jungen Frauen erschüttert Edinburgh. Alle Opfer sind auf dieselbe grausame Weise gestorben. Zur gleichen Zeit tritt der Medizinstudent Will Raven seine Stelle bei dem brillanten und renommierten Geburtshelfer Dr. Simpson an, in dessen Haus regelmäßig bahnbrechende Experimente mit neu entdeckten Betäubungsmitteln stattfinden. Hier trifft Will auf das wissbegierige Hausmädchen Sarah, die jedoch einen großen Bogen um ihn macht und sofort erkennt, dass er ein dunkles Geheimnis mit sich herumträgt.