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Dr. Jean Marmoreo spent her career keeping people alive. But when the Supreme Court of Canada gave the green light to Medical Assistance in Dying (MAiD) in 2016, she became one of a small group of doctors who chose to immediately train themselves in this new field. Over the course of a single year, Marmoreo learns about end-of-life practices in bustling Toronto hospitals, in hospices, and in the facilities of smaller communities. She found that the needed services were often minimal—or non-existent.

In February 2013, Toronto's former mayor, Rob Ford, was caught on video smoking crack cocaine. Weeks later, he was accused of groping a campaign rival; had to leave a gala for being too intoxicated; and was fired as the coach of a high school football team. The events were part of a stream of Rob Ford "mishaps", which include a DUI; accusations of domestic violence; a trial where the Toronto City Council stripped him of his powers; even accusations of murder.

In 1966, a male baby, Chris, was adopted by an upper-middle-class Toronto family. From early childhood, Chris felt ill at ease as a boy and like an outsider in his conservative family. An obsession with sports - running, waterskiing, and cycling - helped him survive what he would eventually understand to be a profound disconnect between his anatomical sexual identity and his gender identity. In his 20s, with the support of newfound friends and family and the medical community, Chris became Kristen.