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When the External Womb Programme is launched, the news is controversial. Hundreds take to the streets in protest, feeling strongly that growing a baby outside of the human body is "unnatural". But thousands more people rejoice: at last, an alternative for those who wish to have children but worry about the physical toll it may take. A chance that throwing a baby-shaped grenade into one's career path might not derail it entirely.

Bill Masen, bandages over his wounded eyes, misses the most spectacular meteorite shower England has ever seen. Removing his bandages the next morning, he finds masses of sightless people wandering the city. He soon meets Josella, another lucky person who has retained her sight, and together they leave the city, aware that the safe, familiar world they knew a mere 24 hours before is gone forever. But to survive in this post-apocalyptic world, one must survive the Triffids, strange plants that years before began appearing all over the world.

At a shadowy company (Karoli Robotics Corporation) owned by a Sillicon Valley billionaire, a scientist named Jim creates an AI that can fool the Turing test at the same time as his colleague, Daniel, successfully synthesizes DNA in a test tube. Daniel's attempts to reanimate dead chimps using his discovery have been unsuccessful, but when his friend Laura Bocelli is killed by being trapped inside a lab freezer, Daniel is presented with the perfect specimen. However, Laura is irreparably brain dead.