Life Science Industry

In Being Mortal, best-selling author Atul Gawande tackles the hardest challenge of his profession: how medicine can not only improve life but also the process of its ending. Medicine has triumphed in modern times, transforming birth, injury, and infectious disease from harrowing to manageable. But in the inevitable condition of aging and death, the goals of medicine seem too frequently to run counter to the interest of the human spirit.

Despite advances in health care, infectious microbes continue to be a formidable adversary to scientists and doctors. Vaccines and antibiotics, the mainstays of modern medicine, have not been able to conquer infectious microbes because of their amazing ability to adapt, evolve, and spread to new places. Terrorism aside, one of the greatest dangers from infectious disease we face today is from a massive outbreak of drug-resistant microbes.

Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor Southern tobacco farmer who worked the same land as her slave ancestors, yet her cells - taken without her knowledge - became one of the most important tools in medicine: The first “immortal” human cells grown in culture, which are still alive today, though she has been dead for more than 60 years. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects.

In their book Abundance, best-selling authors and futurists Peter Diamandis and Steven Kotler tackled grand global challenges, such as poverty, hunger, and energy. Then, in Bold, they chronicled the use of exponential technologies that allowed the emergence of powerful new entrepreneurs. Now the best-selling authors are back with The Future Is Faster Than You Think, a blueprint for how our world will change in response to the next 10 years of rapid technological disruption.

Over his four-decade career, Sid Meier has produced some of the world's most popular video games, including Sid Meier's Civilization, which has sold more than 51 million units worldwide and accumulated more than one billion hours of play. Sid Meier's Memoir! is the story of an obsessive young computer enthusiast who helped launch a multibillion-dollar industry.

For two thousand years, cadavers have been involved in science's boldest strides and weirdest undertakings. They've tested France's first guillotines, ridden the NASA Space Shuttle, been crucified in a Parisian laboratory to test the authenticity of the Shroud of Turin, and helped solve the mystery of TWA Flight 800. For every new surgical procedure, from heart transplants to gender reassignment surgery, cadavers have been there alongside surgeons, making history in their quiet way.

As revelatory as Atul Gawande’s Being Mortal, physician and award-winning author Louise Aronson’s Elderhood is an essential, empathetic look at a vital but often disparaged stage of life. For more than 5,000 years, 'old' has been defined as beginning between the ages of 60 and 70. That means most people alive today will spend more years in elderhood than in childhood, and many will be elders for 40 years or more. Yet at the very moment that humans are living longer than ever before, we’ve made old age into a disease.

In the summer of 1990, fourteen-year-old Trevor Riddell gets his first glimpse of Riddell House. Built from the spoils of a massive timber fortune, the legendary family mansion is constructed of giant, whole trees, and is set on a huge estate overlooking Puget Sound. Trevor’s bankrupt parents have begun a trial separation, and his father, Jones Riddell, has brought Trevor to Riddell House with a goal: to join forces with his sister, Serena, dispatch Grandpa Samuel—who is flickering in and out of dementia...

Since we first heard rumblings about a novel type of pneumonia in Wuhan, China, terms like pandemic, spike protein, viral particles, variants, mRNA vaccines, antibodies, hydroxychloroquine, social distancing, immune response, convalescent plasma, aerosol transmission, and of course, face coverings, have entered our everyday vocabulary. The scientific literature has exploded with studies exploring every facet of COVID-19, but unfortunately the “viral” spread of misinformation about the pandemic has also reached epic proportions.

In gripping prose, one of the world's leading cardiac surgeons lays bare both the wonder and the horror of a life spent a heartbeat away from death. When Stephen Westaby witnessed a patient die on the table during open-heart surgery for the first time, he was struck by the quiet, determined way the surgeons walked away. As he soon understood, this detachment is a crucial survival strategy in a profession where death is only a heartbeat away. In Open Heart, Westaby reflects on over 11,000 surgeries, showing us why the procedures have never become routine and will never be.

At the University of Wisconsin, Dr. Joshua Mezrich creates life from loss, transplanting organs from one body to another. In this intimate, profoundly moving work, he illuminates the extraordinary field of transplantation that enables this kind of miracle to happen every day.

Dr. Arline T. Geronimus coined the term “weathering” to describe the effects of systemic oppression—including racism and classism—on the body. In Weathering, based on more than 30 years of research, she argues that health and aging have more to do with how society treats us than how well we take care of ourselves. She explains what happens to human bodies as they attempt to withstand and overcome the challenges and insults that society leverages at them, and details how this process ravages their health. And she proposes solutions.

In 1920, at the end of the last major pandemic, global life expectancy was just over 40 years. Today, in many parts of the world, human beings can expect to live more than 80 years. As a species, we have doubled our life expectancy in just one century. There are few measures of human progress more astonishing than this increased longevity.

Liz Ianelli, known around the world as Survivor993, spent years at the Family Foundation—labeled an “institution for troubled teens.” The children who went through The Family School like her were good people. They had potential and dreams, but they came out with lifelong trauma: anxious, angry, paranoid, self-hating and in pain. Most of them have suffered lives of hardship, unable to integrate back into society. Hundreds have died, mostly by overdose and suicide. I See You, Survivor is about what really happened at The Family and what continues to happen at thousands of facilities like it.

In Higher Animals, New Yorker science writer Michael Specter explores how MRNA vaccines have transformed the scientific landscape and helped spark a biotechnology revolution. Biology is information, and increasingly, that means digital information. We need to think of biology the way we think about computer code, only instead of bits and bytes, we use the genetic letters: ACGT. The widely-used mRNA COVID vaccines offer the most immediate example of this groundbreaking moment in medical and scientific history.

Jessica Zitter became a doctor because she wanted to be a hero. She elected to specialize in critical care - to become an ICU physician - and imagined herself swooping in to rescue patients from the brink of death. But then during her first code she found herself cracking the ribs of a patient so old and frail it was unimaginable he would ever come back to life. She began to question her choice. Extreme Measures charts Zitter's journey from wanting to be one kind of hero to becoming another - a doctor who prioritizes the patient's values and preferences.

Against a global backdrop of wartime suffering and postwar hope, Borrowing Life gathers the personal histories of the men and women behind the team that enabled and performed the modern medical miracle of the world's first successful organ transplant.

Scientists have long struggled to make pregnancy easier, safer, and more successful. In The Dance of Life, developmental and stem-cell biologist Magdalena Zernicka-Goetz takes us to the front lines of efforts to understand the creation of a human life. She has spent two decades unraveling the mysteries of development, as a simple fertilized egg becomes a complex human being of 40 trillion cells. Zernicka-Goetz's work is both incredibly practical and astonishingly vast.

When a waiting world learned on April 12, 1955, that Jonas Salk had successfully created a vaccine to prevent poliomyelitis, he became a hero overnight. Born in a New York tenement, humble in manner, Salk had all the makings of a 20th-century icon - a knight in a white coat. In the wake of his achievement, he received a staggering number of awards and honors; for years his name ranked with Gandhi and Churchill on lists of the most revered people.

Life sciences companies deliver the most innovative, life changing products in the world. Period. And yet, when it comes to delivering impactful experiences built around patients and healthcare professionals that leverage omnichannel capabilities to commercialize these therapies, our industry struggles to transform (to put it diplomatically). Why? It's because we never took the time to properly educate ourselves on the basic building blocks of omnichannel capabilities and advanced concepts on customer-driven experiences that address stakeholder needs.