Mina is trying to focus on her job as a flight attendant, not the problems of her five-year-old daughter back home or the fissures in her marriage. But the plane has barely taken off when Mina receives a chilling note from an anonymous passenger, someone intent on ensuring the plane never reaches its destination. Someone who needs Mina's assistance and who knows exactly how to make her comply. It's 20 hours to landing. A lot can happen in 20 hours....

Nina Landry awakens on her 40th birthday, anticipating a day filled with excitement. She, her new boyfriend, and her two children are taking a trip - leaving their home on Sandling Island, off the coast of England, for a dream vacation. As soon as her 15-year-old daughter, Charlie, returns from a sleepover, they can get ready to leave. But Charlie doesn’t come home at the expected time. As minutes and then hours tick by, Nina’s annoyance soon changes to concern, and then to a chilling certainty that something terrible has happened.

Anna Hart is a seasoned missing persons detective in San Francisco with far too much knowledge of the darkest side of human nature. When tragedy strikes her personal life, Anna, desperate and numb, flees to the Northern California village of Mendocino to grieve. She lived there as a child with her beloved foster parents, and now she believes it might be the only place left for her. Yet the day she arrives, she learns that a local teenage girl has gone missing.

New friends Sam, Margaret and Diana are thrilled to be getting out of the city for a girls’ weekend - they’ve bonded over their messy divorces, and every mile on the odometer feels like another step towards putting their exes in the past. But when car trouble halfway into their trip strands them in the most unlikely of mountain towns, they come face-to-face with the hurts and betrayals they were so desperate to leave behind. When Diana doesn't return home after a night out, Sam and Margaret's search for her reveals just how little they know about their friend.

When Fiona Lawson comes home to find strangers moving into her house, she's sure there's been a mistake. She and her estranged husband, Bram, have a modern coparenting arrangement: bird's nest custody, where each parent spends a few nights a week with their two sons at the prized family home to maintain stability for their children. But the system built to protect their family ends up putting them in terrible jeopardy. In a domino effect of crimes and misdemeanors, the nest comes tumbling down.

Lex Gracie doesn't want to think about her family. She doesn't want to think about growing up in her parents' House of Horrors. And she doesn't want to think about her identity as Girl A: the girl who escaped, the eldest sister who freed her older brother and four younger siblings. It's been easy enough to avoid her parents - her father never made it out of the House of Horrors he created, and her mother spent the rest of her life behind bars. But when her mother dies in prison and leaves Lex and her siblings the family home, she can't run from her past any longer.

London cycle courier Astrid Bell has known most of her housemates for years, but while they have a tangled history together - romantic pairings, one-night stands, friendships - they each have secrets. Astrid is on her way home one day when her neighbor accidentally knocks her off her bike. Suffering a few bruises, her roommates help her home. The next day, they learn that same neighbor was bludgeoned to death only hours after the accident.

When two young sisters disappear from a strip mall parking lot in a small Pennsylvania town, their devastated mother hires an enigmatic bounty hunter, Alice Vega, to help find the girls. Immediately shut out by a local police department already stretched thin by budget cuts and the growing OxyContin and meth epidemic, Vega enlists the help of a disgraced former cop, Max Caplan. Cap is a man trying to put the scandal of his past behind him and move on, but Vega needs his help to find the girls, and she will not be denied.

In 1977, Claire Lake, Oregon, was shaken by the Lady Killer Murders: Two men, seemingly randomly, were murdered with the same gun, with strange notes left behind. Beth Greer was the perfect suspect - a rich, eccentric 23-year-old woman, seen fleeing one of the crimes. But she was acquitted, and she retreated to the isolation of her mansion.

Newlyweds Sam Statler and Annie Potter are head over heels, and excited to say good-bye to New York city and start a life together in Sam's sleepy hometown upstate. Or, it turns out, a life where Annie spends most of her time alone while Sam, her therapist husband, works long hours in his downstairs office, tending to the egos of his (mostly female) clientele. Little does Sam know that through a vent in his ceiling, every word of his sessions can be heard from the room upstairs.