Andrew Larimer has left his past behind. Rising up the ranks in a New York law firm, and with a heavily pregnant wife, he is settling into a new life far from Kingsport, the town in which he grew up. But when he receives a late-night phone call from an old friend, he has no choice but to return home.

Bryan and Ellie Stockton hope they left behind their demons when they move to their idyllic new home in southern West Virginia. Above all, they want a fresh start for their young son, Derrick, who witnessed the tumultuous first years of their marriage—years that were rife with substance abuse, rage, and resentment. Their bright hope for the future is darkened when a child disappears from their neighborhood. The couple becomes suspicious of a reclusive resident with a degenerative brain disorder.

Deep in the heart of Appalachia stands a crooked farmhouse miles from any road. The Morrows keep to themselves, and it's served them well so far. When girls go missing off the side of the highway, the cops don't knock on their door. Which is a good thing, seeing what's buried in the Morrows' backyard. But 19-year-old Michael Morrow isn't like the rest of his family. He doesn't take pleasure in the screams that echo through the trees.

Max Maurey should be on top of the world. He's a famous horror director. Actors love him. Hollywood needs him. He's making money hand over fist. But it's the 80s, and he's directing cheap slashers for audiences who only crave more blood, not real art. Not real horror. And Max's slimy producer refuses to fund any of his new ideas. But when Max discovers an old camera that filmed a very real Hollywood horror, he knows that he has to use this camera for his next movie. The only problem is that it came with a cryptic warning and sometimes wails.

In the summer of 1994, psychologist Daniel Hill buys a rustic farmhouse nestled in the rolling hills of West Virginia. Along with his wife and teenage daughter, the family uproots their lives in Ohio and moves south. They are initially seduced by the natural beauty of the country setting. That soon changes when they discover a hidden room in the basement with a well, boarded shut and adorned with crucifixes. Local legends about the previous owner being an exorcist come to light, but by then, all Hell has broken loose.

Everyone knows about Ashburn House. They whisper its old owner went mad, and restless ghosts still walk the halls. They say it's the dwelling place of something cruel and sinister. But when Adrienne, desperate and in need of a place to stay, inherits the crumbling old mansion, she only sees it as a lifeline...until darkness falls.

In the lands of Bethel, where the Prophet's word is law, Immanuelle Moore's very existence is blasphemy. Her mother's union with an outsider of a different race cast her once-proud family into disgrace, so Immanuelle does her best to worship the Father, follow Holy Protocol, and lead a life of submission, devotion, and absolute conformity, like all the other women in the settlement. But a mishap lures her into the forbidden Darkwood surrounding Bethel, where the first prophet once chased and killed four powerful witches.

Joe works at a facility that performs human experimentation. His work just followed him home. The government wanted to unlock hidden abilities in the human mind. They put subjects in extreme sensory deprivation. All the test subjects went violently insane. But the research continued. Today it has been perfected. Almost perfected.

Since the 1970s, FantasticLand has been the theme park where "Fun is Guaranteed!" But when a hurricane ravages the Florida coast and isolates the park, the employees find it anything but fun. Five weeks later, the authorities who rescue the survivors encounter a scene of horror. Photos soon emerge online of heads on spikes outside of rides and viscera and human bones littering the gift shops, breaking records for hits, views, likes, clicks, and shares.

After the loss of a child along with a slew of agonizing misfortunes, Nick and Jess decide to end their lives. Unable to cope with the misery that fills their days, they commit one last act together and die in loving relief. But when Nick wakes up, he soon realizes that death isn't the gentle darkness he expected. Panicked and horrified, he struggles to understand the twisted abominations and hellish world he's now trapped in.