A clear and practical introduction to Organ-on-Chip technology and why microphysiological systems outperform classic 2D and even 3D cell culture models. Learn which mechanical and material parameters truly define chip stability, transport behavior and barrier function.

A concise look at the most common reasons why 3D spheroid cultures fail — and the practical framework to improve uniformity, aggregation behavior and reproducibility. Ideal for anyone working with 3D assays, oncology models, barrier systems or advanced in-vitro testing.

A quick, expert-driven look at one of the most overlooked challenges in cell culture: the hidden cost of inconsistent materials and workflows. Learn how small quality shifts impact your results — and how to build more reliable, reproducible processes.

Today I want to start with one of the most common questions I hear from researchers, diagnostic developers and viral vector teams:
“Should we use FBS or Human Serum — and does it actually make a difference?”

And the short answer is:
Yes. It makes a big difference.
But not always in the way people expect.

Most labs choose serum based on tradition.
“We’ve always used FBS.”
Or: “We switched to Human Serum once and it didn’t work.”

But when you look closer, you realize something important:
The choice between FBS and Human Serum isn’t about which one is “better,” but about what you need to achieve in your specific model.