Épisodes

  • Episode 88: In the clinic - Metastatic Renal Cancer with Professor Ricky Frazer (part 1/2)
    Feb 5 2026

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    Join us is as we celebrate Kidney Cancer week with a Masterclass walk through metastatic Renal Cancer with Professor Ricky Frazer from Velindre Cancer Centre.

    Ricky is a co-host of the hugely successful Immunobuddies podcast and has a vast experience in immunotherapy management.

    We look at the indications for immunotherapy versus anti-VEGF TKI therapy.

    Should we just accept anti-VEGF TKI monotherapy in Favourable Risk patients?

    When should we try IO/IO combination versus IO/TKI combinations in the first line setting?

    All this whilst Ricky looks to put John in his place!!

    Enjoy



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    28 min
  • Episode 87: The Landscape for Metastatic Endometrial Cancer with Dr Gemma Eminowicz (Part 2/2)
    Jan 29 2026

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    Join us for Part 2 of our Metastatic Endometrial Cancer special with the amazing Dr Gemma Eminowicz from University College London Hospital.

    In episode 1 we looked at molecular profiling and immunotherapy.

    In this episode we explore the role of;

    - hormone therapy

    - Antibody drug conjugates

    - PARP inhibitors

    Endometrial cancer is taking off in terms of new and exciting treatment options.

    Gemma does an amazing job talking us through them.

    Enjoy.

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    30 min
  • Episode 86: The Metastatic Endometrial Cancer landscape with Dr Gemma Eminowicz (1/2)
    Jan 22 2026

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    Dr Gemma Eminowicz returns for 2026!!

    Join us as we discuss the metastatic endometrial cancer landscape with Simply Oncology 'friend of the show' Dr Gemma Eminowicz from University College Hospital London.

    Advanced endometrial cancer is so much more than carboplatin and paclitaxel. It now has the complete range of oncological treatments;

    - Chemotherapy

    - Immunotherapy

    - Antibody Drug Conjugates

    - Hormone therapy

    - Targeted therapy

    - Radiotherapy

    We look at how the molecular testing in endometrial cancer has shaped advanced endometrial cancer therapy.

    We look at the arrival of chemo-immunotherapy in the MMRd group and now in the MMRp patient group.

    In the MMR proficient group we discuss the merits of 1st line Chemo-immunotherapy versus sequencing treatment to allow potential VEGF targeted therapy.

    Gemma shares her invaluable experience and helps Mike understand advanced endometrial cancer.


    Enjoy!!

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    22 min
  • Episode 85: Future directions in advanced Oesophago-Gastric cancer with Dr Lizzy Smyth
    Jan 13 2026

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    We return for part 2 of our overview on metastatic oesphago-gastric cancer.

    Join us as we welcome back Dr Lizzy Smyth from Oxford University Hospitals.

    We look at the importance of nutritional support.

    We discuss future directions such as CAR-T therapy

    Lizzy mocks John (again!!)

    A brilliant finish to our OG masterclass from Lizzy.

    Enjoy!

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    20 min
  • Episode 84; In the Clinic - Discussing metastatic Oesophago-Gastric Cancer with Dr Lizzie Smith
    Jan 5 2026

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    Dr Lizzie Smith from Oxford University Hospitals gives us a an amazing 2 part overview of management of metastatic Oesophago-Gastric cancer.

    We discuss molecular testing and therapy options in metastatic OG cancer🧬
    HER2
    PDL 1
    Claudin 18.2

    Lizzy is a hugely respected figure in OG cancer and key clinical trialist!

    John gets put in his place by Lizzy on several occasions!!

    Lizzy has a way of describing things that even John could understand!!

    Part 1 of 2 in this metastatic OG masterclass.


    Enjoy!

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    25 min
  • Episode 83: In the Clinic - Part 2 of PARPi in prostate cancer with Professor Rob Jones
    Dec 24 2025

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    Happy New Year!!!

    WE return in 2026 to complete our overview of PARPi in prostate cancer with the peerless Professor Rob Jones.

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    22 min
  • Episode 82: in the Clinic - PARP inhibitors in metastatic Prostate Cancer with Professor Rob Jones
    Dec 24 2025

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    Join us as we unwind in the Christmas Holiday period with a masterful overview of PARP inhibitors in metastatic prostate cancer with Professor Rob Jones.

    Rob is an old friend of the show and is amazing at setting the scene for who & when PARP inhibitors can be useful in metastatic prostate cancer.



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    28 min
  • Episode 81: Part 2 Management of menopause and breast cancer with Dr Rebecca Bowen
    Dec 19 2025

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    Welcome back!

    In part 1 we discussed the major effects of menopause and how these can be worsened by hormonal medications given to treat breast cancer and the impact these can have on patients completing treatment as planned.

    In this episode we welcome back Dr Rebecca Bowen and discuss practical advice on managing these symptoms including a link to what will be a vital resource for all clinicians in Oncology and Primary Care: the Meno.Pause app.


    Link below, download today!

    Meno.Pause App


    We wish all our wonderful listeners and guests a very Merry Christmas, thank you as always for tuning in,


    John and Mike.

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    21 min