Genetics Health

Cystic fibrosis was once a mysterious disease that killed infants and children. Now it could be the key to healing millions with genetic diseases of every type - from Alzheimer's and Parkinson's to diabetes and sickle cell anemia. Told from the perspectives of the patients, families, physicians, scientists, and philanthropists fighting on the front lines, Breath from Salt is a remarkable story of unlikely scientific and medical firsts, of setbacks and successes, and of people who refused to give up hope....

Do you live with a chronic, debilitating, yet invisible condition? You may feel isolated, out of step, judged, lonely, or misunderstood - and that's on top of dealing with your actual illness. Take heart. You are not alone, although sometimes it can feel that way. Written by a blogger who suffers from an invisible chronic illness, Surviving and Thriving with an Invisible Chronic Illness offers peer-to-peer support to help you stay sane, be your own advocate, and get back to living your life. This compelling guide is written for anyone suffering with an illness no one can see.

One morning, Tophs, Taylor Harris’ round-cheeked, lively 22-month-old, wakes up listless, only lifting his head to gulp down water. She rushes Tophs to the doctor, ignoring the part of herself, trained by years of therapy for generalized anxiety disorder, that tries to whisper that she’s overreacting. But at the hospital, her maternal instincts are confirmed: something is wrong with her boy, and Taylor’s life will never be the same.

A fascinating survey of the forces that shape who we are and how we act - from the author of The Calculus Diaries. Following her previous tours through the worlds of physics ( Black Bodies and Quantum Cats) and calculus ( The Calculus Diaries), acclaimed science writer Jennifer Ouellette now turns her attention to the mysteries of human identity and behavior with Me, Myself, and Why.

Homo sapiens emerged as a species about 200,000 years ago and soon—with fire, simple tools, and an egalitarian social system—we inhabited every continent. But now our infinitely elaborated tools and our highly non-egalitarian social system threaten sustainability. Many at the bottom lose the desire to live, committing suicide or succumbing to drugs, alcohol, and obesity. What is Health? explains from the bottom up—molecules to society—how we reached this point.

You are just 10% human. For every one of the cells that make up the vessel that you call your body, there are nine impostor cells hitching a ride. You are not just flesh and blood, muscle and bone, brain and skin, but also bacteria and fungi. Over your lifetime, you will carry the equivalent weight of five African elephants in microbes. You are not an individual but a colony. Until recently, we had thought our microbes hardly mattered, but science is revealing a different story, one in which microbes run our bodies and becoming a healthy human is impossible without them.

Did you know women walk more, eat less, socialize more, meet more men, dance more, and flirt more when they're ovulating? Or that PMS may have evolved to get rid of boyfriends with unfit sperm? Behind the "fickle" differences in what women find sexy about men, or what they like to wear, there's a hidden adaptive intelligence shaped over eons. Rather than making women irrational - as the conventional and irredeemably sexist wisdom goes - the female hormonal cycle has been exquisitely fine-tuned to give women the advantages they needed to succeed in our ancestral environments, and perhaps also today.

Why do three out of four professional football players go bankrupt? How can illiterate jungle dwellers pass a test that tricks Harvard philosophers? And why do billionaires work so hard - only to give their hard-earned money away? When it comes to making decisions, the classic view is that humans are eminently rational. But growing evidence suggests instead that our choices are often irrational, biased, and occasionally even moronic. Which view is right - or is there another possibility?

For readers of Being Mortal and Modern Death, an ICU and Palliative Care specialist offers a framework for a better way to exit life that will change our medical culture at the deepest level In medical school, no one teaches you how to let a patient die. Jessica Zitter became a doctor because...

Around 250,000 people have had their genomes sequenced, and scientists expect that number to rise to one billion by 2025. Professor Steven J. Heine argues that the first thing we will do on receiving our DNA test results is to misinterpret them completely. Despite breathless (often lightly researched) media coverage about newly discovered "cancer" or "divorce" or "IQ" genes, the prospect of a DNA test forecasting how your life is going to turn out is vanishingly small.

Why are we the way we are? Why do some of us find it impossible to calm a quick temper or to shake anxiety? The debate has always been divided between nature and nurture, but as psychology professor Daniel P. Keating demonstrates in Born Anxious, new DNA science points to a third factor that allows us to inherit both the nature and the nurture of previous generations - with significant consequences.

In this eye-opening work, Graziano accessibly explores how this sense of an inner being led to empathy and formed us into social beings. The theory may point the way to engineers for building consciousness artificially. Graziano discusses what a future with artificial consciousness might be like, including both advantages and risks, and what AI might mean for our evolutionary future.

A respected immunologist, allergist, and functional medicine doctor breaks down the latest science on immunity, offering a program to help you identify your unique immunotype and balance your system for optimal health and longevity. To most of us, the immune system is seemingly unknowable—it's...

In this startling study of human emotion, Dacher Keltner investigates an unanswered question of human evolution: If humans are hardwired to lead lives that are "nasty, brutish, and short," why have we evolved with positive emotions like gratitude, amusement, awe, and compassion that promote ethical action and cooperative societies? Born to Be Good takes us on a journey through scientific discovery, personal narrative, and Eastern philosophy.

All of us would like to live longer, or to slow the debilitating effects of age. In How We Age, Coleen Murphy shows how recent research on longevity and aging may be bringing us closer to this goal. Murphy, a leading scholar of aging, explains that the study of model systems, particularly simple invertebrate animals, combined with breakthroughs in genomic methods, have allowed scientists to probe the molecular mechanisms of longevity and aging.

For readers of Hidden Valley Road and Patient H.M., an “intimate and compassionate portrait” (Grace M. Cho) of the Genain quadruplets, the harrowing violence they experienced, and its psychological and political consequences.​ In 1954, researchers at the newly formed National Institute of...

A groundbreaking study of the lifelong effects of near-death experiences in the newly born, babies, toddlers, and children up to age five Draws on interviews with nearly 400 childhood experiencers, both fully matured and young, as well as more than 40 years of NDE research involving over 5...

A Sick Life chronicles Tionne's journey from a childhood spent in and out of the hospital, told she wouldn't live to see 30 or have children, to becoming the superstar musician who is still living out her life's dream of performing. For the first time, Tionne will tell her full life story - the diagnosis, the tumultuous rise to fame, the life in the spotlight, and the hard-fought advocacy work.

The burgeoning new science of epigenetics offers a cornucopia of insights - some comforting, some frightening. For example, the male fetus may be especially vulnerable to certain common chemicals in our environment, in ways that damage not only his own sperm but also the sperm of his sons. And it’s epigenetics that causes identical twins to vary widely in their susceptibility to dementia and cancer. But here’s the good news: unlike mutations, epigenetic effects are reversible. Indeed, epigenetic engineering is the future of medicine.

“There is no good reason why human societies should not be described and explained with the same precision and success as the rest of nature.” Thus argues evolutionary psychologist Pascal Boyer in this uniquely innovative book. Integrating recent insights from evolutionary biology, genetics, psychology, economics, and other fields, Boyer offers precise models of why humans engage in social behaviors such as forming families, tribes, and nations, or creating gender roles.