Imagine a killer who thinks, "What is the worst thing anyone has ever done?"—and then goes far beyond it. Now imagine four women—a police detective, an assistant DA, a reporter, and a medical examiner—who join forces as they sidestep their bosses to track down criminals. Known as the Women's Murder Club, they are pursuing a murderer whose twisted imagination has stunned an entire city. Their chief suspect is a socially prominent writer, but the men in charge won't touch him. On the trail of the most terrifying and unexpected killer ever, they discover a shocking surprise.

"I'm not on trial. San Francisco is". An accused murderer called Kingfisher is about to go on trial for his life. Or is he? By unleashing unexpected violence on the lawyers, jurors, and police involved in the case, he has paralyzed the city. Detective Lindsay Boxer and the Women's Murder Club are caught in the eye of the storm. Now comes a courtroom shocker you will never see coming.

Attorney Rhonda Bird returns home after a long estrangement when she learns her father has died. There she makes two important discoveries: Her father stopped being an accountant and had opened up a private detective agency, and she has a teenage half sister named Baby. Baby brings in a client to the detective agency, a young man who claims he was abducted.

Alex Cross is a homicide detective with a PhD in psychology. He works and lives in the ghettos of D. C. and looks like Muhammad Ali in his prime. He's a tough guy from a tough part of town who wears Harris Tweed jackets and likes to relax by banging out Gershwin tunes on his baby grand piano. But he also has two adorable kids of his own, and they are his own special vulnerabilities. Jezzie Flanagan is the first woman ever to hold the highly sensitive job as supervisor of the Secret Service in Washington.

There's a killer on the loose in San Francisco, and he's stalking newlyweds. When the usual procedures to stop him don't work, four women, each holding a piece of the puzzle, form a Women's Murder Club to collaborate outside the box and pursue the case. 1st to Die is the start of a new series of crime thrillers from James Patterson.