Four young women have been found murdered—tortured and strangled in their own beds—all victims of the same brilliant monster. Using a skilled hand and the latest technology in forensic medicine, Kay Scarpetta begins the process of gathering the microscopic clues the latest battered body has to give.

The "maddog" murderer who is terrorizing the Twin Cities is two things: insane and extremely intelligent. He kills for the pleasure of it and thoroughly enjoys placing elaborate obstacles to keep police befuddled. Each clever move he makes is another point of pride. But when the brilliant Lieutenant Lucas Davenport, a dedicated cop and a serial killer's worst nightmare, is brought in to take up the investigation, the maddog suddenly has an adversary worthy of his genius.

Over twenty years ago, the heiress Patricia Lockwood was abducted during a robbery of her family's estate, then locked inside an isolated cabin for months. Patricia escaped, but so did her captors - and the items stolen from her family were never recovered. Until now. On the Upper West Side, a recluse is found murdered in his penthouse apartment, alongside two objects of note: a stolen Vermeer painting and a leather suitcase bearing the initials WHL3. For the first time in years, the authorities have a lead - with the suitcase and painting both pointing them toward one man.

When a boy is found dead with the skin of a hare’s head in his hand, everyone knows who killed him—Willis Newland, just released from prison after serving twenty years for an identical murder. But what if everyone’s wrong? Detective Colly Newland reluctantly agrees to investigate a case that seems to involve the whole town, including her dead husband’s extended family. But the deeper she digs, the more secrets she unearths.

Thirty years ago, Wilde was found as a boy living feral in the woods, with no memory of his past. Now an adult, he still doesn't know where he comes from, and another child has gone missing. No one seems to take Naomi Pine's disappearance seriously, not even her father - with one exception. Hester Crimstein, a television criminal attorney, knows through her grandson that Naomi was relentlessly bullied at school. Hester asks Wilde - with whom she shares a tragic connection - to use his unique skills to help find Naomi.