The rich and powerful Guise family was one of the most treacherous and bloodthirsty in sixteenth-century France. They whipped up religious bigotry, overthrowing the king. They ruled Scotland for nearly 20 years through Mary Queen of Scots, plotting to invade England and overthrow Elizabeth I. And they unleashed the bloody Wars of Religion, playing a crucial role in the murder of 4,000 Protestants in the infamous Saint Bartholomew's Day Massacre.

In this final episode for Not Just the Tudors' Tudor True Crime month, Professor Suzannah Lipscomb talks to Professor Stuart Carroll - author of Martyrs and Murderers: The Guise Family and the Making of Europe - about this cultivated, charismatic and violent dynasty.

MORE:

Catherine d'Medici: Serpent Queen >

Mary Queen of Scots' Lost Letters Decoded >

Presented by Professor Suzannah Lipscomb. Edited by Stuart Beckwith and produced by Rob Weinberg. The senior producer is Anne-Marie Luff.

All music courtesy of Epidemic Sounds.

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