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Page de couverture de LMC #53 | Gwen Orilio: How a High School Teacher Defied a Stage IV Diagnosis

LMC #53 | Gwen Orilio: How a High School Teacher Defied a Stage IV Diagnosis

LMC #53 | Gwen Orilio: How a High School Teacher Defied a Stage IV Diagnosis

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 This episode is sponsored by Lightstone Direct LLC. Lightstone Direct LLC connects you to institutional-quality real estate investments backed by a $12-billion AUM firm that co-invests alongside you—your partner in building lasting wealth. All investments involve risk. Please visit LightstoneDirect.com for a full list of disclosures.---When Gwen Orilio was diagnosed with stage IV lung cancer at 34—just 18 months after her daughter was born—she was told she might not live long enough to see her child grow up.Ten years later, Gwen is still teaching high school math, coaching track, raising her daughter, and flying to Boston for clinical trials that continue to save her life.In this heartfelt episode, Gwen shares how she faced her diagnosis head-on, chose immediate treatment over preserving fertility, and became one of the earliest participants in phase-one targeted therapy trials for the ROS1 mutation. She discusses the science behind her treatments, the role of persistence, and why she keeps teaching—to stay grounded and to model resilience for her students.With humor, humility, and gratitude, Gwen also opens up about parenting through uncertainty, advocating for cancer funding, and finding beauty in small moments. Her story redefines what it means to live with cancer—not just to survive, but to thrive and make memories that last.Highlights🧬 A Diagnosis Through an Eye Exam: How a simple vision check revealed a tumor that led to a life-changing discovery.✈️ Flying for Hope: Why Gwen travels monthly to Boston for cutting-edge clinical trials. 👩‍🏫 Teaching Through Treatment: Staying in the classroom helped her maintain purpose and normalcy.💪 Resilience & Advocacy: How she uses her experience to educate others about lung cancer and raise awareness for non-smoker cases.💡 Redefining the Future: Opening a Roth IRA, planning trips, and embracing life despite uncertainty.Top 3 TakeawaysScience Saves Lives. Targeted therapies and clinical trials can turn a terminal diagnosis into a manageable condition.Live While You Can. None of us know how much time we have—so spend it on memories, not regrets.Advocacy Matters. Cancer awareness and patient persistence push research and funding forward for everyone.Guest BioGwen Orilio is a high school math teacher in Clayton, North Carolina, who has been living with stage IV lung cancer for over a decade. Diagnosed at 31 with a grim prognosis, she has defied expectations—navigating years of cutting-edge treatments that have transformed her diagnosis into a chronic condition.A former collegiate track athlete, Gwen competed in the long jump at SUNY Geneseo, where she met her husband, Justin Orilio. After graduating in 2005, she began her career in education and has continued to inspire both in and outside the classroom.Gwen hasn’t let cancer slow her down. She maintains a full schedule teaching, coaching, and raising her 12-year-old daughter, while also participating in clinical trials that advance research for ROS1-positive lung cancer. With her optimism and advocacy, Gwen continues to inspire others and raise awareness about the critical need for funding and innovation in lung cancer research.About the Host:Dr. Peter Crane is a board-certified physician, educator, and storyteller with a heart for service and a calling to spotlight doctors who make a difference—in their communities, in medicine, and in the lives they touch.Through Doctors Making a Difference, he brings you into intimate conversations with physicians who have overcome challenges, redefined success, and found purpose in and beyond the clinic. His goal is simple: to help more doctors stay in medicine by showing them what's possible.About the Show:Doctors Making a Difference is more than a podcast—it’s a movement to highlight the good, the gritty, and the deeply human side of medicine.In every episode, Dr. Peter Crane interviews physicians whose stories defy the script. From burnout recovery to bold career pivots, health challenges to quiet leadership, this show honors the truth that healing begins with connection—and doctors, too, deserve to be whole.Visit: doctorsmakingadifference.comLMC Series Note:Living with Metastatic Cancer (LMC) explores the science, decisions, and day-to-day realities of life with advanced disease—through candid physician–patient conversations. The Doctors Making a Difference Podcast is for informational purposes only and does not substitute for medical, legal, or professional advice. Always consult appropriate experts regarding your unique circumstances. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
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