It’s Valentine’s Day weekend, and Charlotte and Seth are not looking for romance. Armed with emotional-support bear spray, Charlotte is in self-imposed isolation and on guard from men. Having a stalker can do that to a person’s nerves. Just across the hall and giving off woodsy vibes is Seth, a recently divorced arborist. As in today recently. Heights, he’s fine with. Trust? Not so much.

Daisy Shoemaker can’t sleep. With a thriving cooking business, full schedule of volunteer work, and a beautiful home in the Philadelphia suburbs, she should be content. But her teenage daughter can be a handful, her husband can be distant, her work can feel trivial, and she has lots of acquaintances, but no real friends. Still, Daisy knows she’s got it good. So why is she up all night?

Welcome to the most tumultuous summer of the 20th century. It's 1969, and for the Levin family, the times they are a-changing. Every year, the children have looked forward to spending the summer at their grandmother's historic home in downtown Nantucket. But like so much else in America, nothing is the same.

Myrna, Leonie, and Chrissy meet every Thursday to sample fine cheeses, to reminisce about their former lives as professors, and lately, to muse about murder. Decades ago, a vicious cabal of male poets contrived—quite publicly and successfully—to undermine the writing career, confidence, and health of their dear friend Fern. Now, after Fern has taken a turn for the worse, her three old friends decide that it’s finally time to strike back—in secret, of course, since Fern is far too gentle to approve of a vendetta.

Kezia Cooper Hobson, recently widowed, arrives in New York from San Francisco. Determined to make a fresh start, she has just completed the sale of her Pacific Heights home, not to mention her husband's venture capital firm, and in doing so, is also freed from her responsibility as a board member of the company. Bringing with her only a few personal treasures, she is excited to move into the blank slate of a beautiful midtown penthouse, in the city that she has always loved. It is also where her two adult daughters now live.