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Dementia Researcher

Dementia Researcher

Auteur(s): Dementia Researcher
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 A biweekly podcast for early career researchers, bringing together fantastic guests to discuss their research, careers + much more. Dedicated to sharing the science, encouraging collaborations, attracting more people to the field, and supporting those already here to succeed. Brought to you by https://www.dementiaresearcher.nihr.ac.uk at University College London, in association with Alzheimer's Association, Alzheimer's Research UK, Alzheimer's Society and Race Against Dementia - everything you need, all in one place. supporting early career researchers across the world Register today to recieve weekly bulletins, with news, funding opportunities, jobs, and events.All rights reserved Science
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  • Detecting UTIs Early in Dementia

    Detecting UTIs Early in Dementia
    Feb 7 2026
    In this episode of the Dementia Researcher podcast, host Adam Smith chats with with Professor Paul Freemont and researcher Tom Adam from the UK Dementia Research Institute at Imperial College London to discuss the critical issue of urinary tract infections (UTIs) in individuals living with dementia. The conversation highlights the complexities of diagnosing UTIs in people living with dementia, where communication barriers and atypical presentations often lead to misdiagnosis and unnecessary hospitalisations. The guests emphasise the urgent need for improved detection methods, as UTIs can exacerbate cognitive decline and lead to severe health complications. They talk about their work to develop and introduce an innovative novel point-of-care diagnostic device designed specifically for dementia patients, which aims to facilitate early detection of UTIs in a home and care home setting, thereby reducing the reliance on traditional symptom reporting and hospital visits. Key takeaways: 🔹UTIs are a major cause of hospital admission and sudden decline in people living with dementia. 🔹Diagnosing UTIs is harder in dementia because symptoms are often not recognised or communicated. 🔹Current testing methods can be slow and sometimes lead to overuse of antibiotics. 🔹New home based rapid testing technology aims to detect infections earlier and closer to where care happens. 🔹Earlier detection could reduce hospital stays and improve quality of life. 🔹Future monitoring of urine biomarkers could help predict infections before symptoms appear. -- A transcript of this show, links and show notes and profile on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk -- Follow us on social media: https://www.instagram.com/dementia_researcher/ https://www.facebook.com/Dementia.Researcher/ https://www.twitter.com/demrescommunity https://www.linkedin.com/company/dementia-researcher https://www.bsky.app/profile/dementiare…archer.bsky.social -- Download and Register with our Community App: https://www.onelink.to/dementiaresearcher Chapters 00:00 Introduction to UTIs in Dementia 04:15 The Seriousness of UTIs in Dementia 18:31 Innovative Approaches to UTI Detection 22:00 Engineering a Diagnostic Device for Home Use 27:04 Innovative UTI Detection Technology 29:41 The Vision for Home Testing 31:40 Personal Motivations Behind the Research 34:40 Understanding the Urinary Microbiome 37:53 Designing the UTI Detection Device 44:20 Testing in Clinical Environments 50:57 Barriers to Market Entry 54:03 Community Awareness and Support 58:46 Outro
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    59 min
  • Three Researchers. One Disease. Lewy Body Dementia

    Three Researchers. One Disease. Lewy Body Dementia
    Jan 24 2026
    In this episode of the Dementia Researcher Podcast, we focus on Lewy body dementia and why it remains one of the most misunderstood and frequently misdiagnosed forms of dementia. Released ahead of Lewy Body Dementia Day on 28 January, the conversation explores what Lewy body dementia is, how it sits between existing diagnostic categories, and why it often takes years for people to receive the right diagnosis. -- Host Dr Sam Moxon is joined by three researchers working on Lewy body dementia from very different angles: 🔹Dr Ece Bayram, Assistant Research Professor at the University of Colorado Anschutz, whose work explores differences in risk, progression and diagnosis across sex, gender, ethnicity and race 🔹Dr Joe Kane, Consultant Psychiatrist and Clinical Lecturer, who combines clinical care with research into diagnosis, service delivery and clinical trials 🔹Dr David Koss, Lecturer and Group Lead at the University of Dundee, studying the cellular and molecular mechanisms underlying Lewy body dementia -- Together, they unpack why Lewy body dementia does not follow a neat clinical pathway, how overlapping symptoms can lead to confusion with Alzheimer disease or Parkinson disease, and why uncertainty in diagnosis affects everything from care planning to research outcomes. The discussion highlights the real world consequences of misdiagnosis, including inappropriate treatments, faster than expected progression, and the emotional toll on families and care partners. The guests also reflect on how limited awareness of Lewy body dementia continues to shape health services, research recruitment and public understanding. Across the episode, a clear theme emerges: Lewy body dementia cannot be understood from a single perspective. Clinical insight, biological research and population level studies all need to connect if progress is to be made. The conversation also explores promising areas of research, including improvements in clinical detection, the development of practical diagnostic tools, the importance of inclusive research populations, and emerging biological findings that may point towards future therapeutic targets. -- Key takeaways 🔹Lewy body dementia includes dementia with Lewy bodies and Parkinson disease dementia 🔹Symptoms extend beyond memory and can include hallucinations, sleep disturbance, fluctuations and movement changes 🔹Diagnosis is frequently delayed due to overlapping features with other dementias 🔹Misdiagnosis can lead to harmful treatments and inappropriate care planning 🔹Care partners play a central role in both diagnosis and ongoing support 🔹Research cohorts often lack diversity, limiting understanding of the 🔹Cellular mechanisms such as alpha synuclein dysfunction remain an important area of study 🔹Early and accurate diagnosis improves care, planning and research quality 🔹Multidisciplinary collaboration is essential to understanding the disease 🔹Public awareness is key to improving detection, funding and outcomes -- A transcript of this show, links and show notes and profile on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk -- Follow us on social media: https://www.instagram.com/dementia_researcher/ https://www.facebook.com/Dementia.Researcher/ https://www.twitter.com/demrescommunity https://www.linkedin.com/company/dementia-researcher https://www.bsky.app/profile/dementiare…archer.bsky.social -- Download and Register with our Community App: https://www.onelink.to/dementiaresearcher
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    47 min
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