Big news! An American biotech company announced this week that they have brought the dire wolf back from extinction! We’ve honoured this great achievement by watching the prophetic film Dire Wolf (2009), a gory werewolf movie in which an American biotech company brought back the dire wolf from extinction... to create a military bioweapon! We’ve got our eyes on you, Colossal Biosciences...

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In this episode:

Watch Dire Wolf (2009) on Tubi: https://tubitv.com/movies/641656/dire-wolf

The Dire Wolf (Aenocyon dirus): https://tarpits.org/stories/our-evolving-understanding-dire-wolves

Bone Clones Dire Wolf Skull: https://boneclones.com/product/dire-wolf-skull-tarpit-finish-BC-020T

Colossal Biosciences: https://colossal.com/

Colossal’s Dire Wolf preprint on BioRxiv: https://www.biorxiv.org/content/10.1101/2025.04.09.647074v1.abstract

Perri et al. (2021) Dire wolves were the last of an ancient New World canid lineage: https://doi.org/10.1038/s41586-020-03082-x

Janczewski et al. (1992) Molecular phylogenetic inference from saber-toothed cat fossils of Rancho La Brea: https://doi.org/10.1073/pnas.89.20.9769

Hank Green – They Didn’t Make Dire Wolves, They Made Something...Else: https://www.youtube.com/watch?v=Ar0zgedLyTw

Beth Shapiro (2020) How to Clone a Mammoth: https://press.princeton.edu/books/paperback/9780691209005/how-to-clone-a-mammoth