They started off by introducing themselves as The Three Horsemen of the Apocalypse - what could possibly go wrong!! Declan couldn't resist the opportunity to invite three very eminent radiation oncologists into the studio when they all happened to be in Melbourne, even if he was particularly outnumbered while Renu was away! Vedang Murthy (Tata Memorial, India), Andrew Loblaw (Sunnybrook Hospital, Canada), and Sarat Chander (Peter Mac, Melbourne) are all highly specialised in prostate radiation, so Declan invited them into the GU Cast studio to pick their brains on three big areas in prostate radiation:
1. Hypofractionation in 2025 - Who and How?
2. Who needs ADT and for how long when having prostate radiation?
3. Metastasis-directed therapy for oligometastatic disease - is there any point??

Tune in to find out how Urologist Declan Murphy fared up against these three Radiation Oncologists!!! Even better on our YouTube channel

This podcast is supported by our Bronze Partner, Icon Cancer Centre.

We never need an excuse to visit Sydney, and for sure when one of our favourite meetings of the year is in the Harbourside City then count us in! The Annual Meeting of ANZUP is something we try and get to every year and have really enjoyed bringing you highlights. This year we catch up with some international faculty including Roger Li (Moffitt Cancer Centre, USA), ANZUP Prostate Cancer Committee bosses Lisa Horvath (Chris O'Brien Lifehouse) and Jarad Martin (Genesis Care), Dickon Hayne (Fiona Stanley Hospital) regarding his NMICB RCT, and Bernie Reilly (Prostate CAncer Foundation of Australia) about some fantastic resources for prostate cancer patients.

Big congrats to all at ANZUP for another excellent meeting and for all they do for GU oncology in Australia and New Zealand.

PS - apologies for some sub-standard audio on this one.

GU Cast Conference Highlights are supported by our Conference Highlights Partner, Bayer.

Episode 2 of our monthly GU Cast Journal Club and today we focus on two key papers from recent times - the TRANSLATE trial of transperineal vs transrectal biopsy, and Keynote-564 on the role of adjuvant pembrolizomab following nephrectomy.
After great feedback from last month's launch episode, we are delighted to welcome back our GU Cast Journal Club Editors, Dr Carlos Delgado (Melbourne, AUS), and Dr Elena Berg (Munich, GER), along with main GU Cast Hosts, Renu Eapen and Declan Murphy

Links to papers and previous podcasts below:
1. Local anaesthetic transperineal biopsy versus transrectal prostate biopsy in prostate cancer detection (TRANSLATE): a multicentre, randomised, controlled trial Lancet Oncology 2025
GU Cast on TRANSLATE

2. Overall Survival with Adjuvant Pembrolizumab in Renal-Cell Carcinoma NEJM 2024
GU Cast on K-564 OS paper

GU Cast Journal Club is supported by our Partner, MSD, through an unrestricted educational grant.

Even better on our YouTube channel

About GU Cast Journal Club:
Each month, two papers are discussed, each of which are of importance to the GU Oncology community. These may be recent papers, or occasionally we will chose a classic landmark paper in GU Oncology
. The objective is to draw attention to important papers in GU Oncology, and critique these in a robust manner
. The key target audience is trainees working in Urology, Medical Oncology, Radiation Oncology, Nuclear Medicine, and diagnostic specialties such as Radiology and Pathology. But any of our regular audience are likely to enjoy this Journal Club series.