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Inside the Ketamine Therapy Craze

Inside the Ketamine Therapy Craze

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In "Inside the Ketamine Therapy Craze," Dr. Ben Synth delivers a comprehensive exploration of ketamine's remarkable evolution from battlefield anesthetic to cutting-edge depression treatment. This episode unpacks ketamine's unique pharmacological profile and how its NMDA receptor antagonism creates both its dissociative effects and rapid-acting antidepressant properties through enhanced neuroplasticity. Listeners will discover the diverse landscape of ketamine treatment options—from traditional IV infusion clinics to FDA-approved Spravato and the emerging at-home telehealth models—along with the varied patient experiences and integration practices that maximize therapeutic outcomes. Dr. Ben examines ketamine's impressive efficacy for treatment-resistant depression and suicidal ideation, while thoughtfully addressing concerns about access, long-term effects, and regulatory challenges in this rapidly evolving field. The episode frames ketamine therapy as both a vital innovation for patients who've failed conventional treatments and a preview of the broader psychedelic medicine renaissance, raising profound questions about our approach to consciousness and mental healthcare.

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