Page de couverture de March 2025: The Impact of Xanomeline and Trospium Chloride on Cognitive Impairment in Acute Schizophrenia: Replication in Pooled Data From Two Phase 3 Trials

March 2025: The Impact of Xanomeline and Trospium Chloride on Cognitive Impairment in Acute Schizophrenia: Replication in Pooled Data From Two Phase 3 Trials

March 2025: The Impact of Xanomeline and Trospium Chloride on Cognitive Impairment in Acute Schizophrenia: Replication in Pooled Data From Two Phase 3 Trials

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Dr. William Horan (Bristol Myers Squibb) joins AJP Audio to discuss a newly approved, novel treatment for schizophrenia spectrum disorder, which has potential impacts for cognition in patients. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin puts the rest of the March issue into context.

  • 00:45 Horan interview
  • 03:15 Novel mechanism of action in the treatment of schizophrenia
  • 05:39 Side effect profiles
  • 07:20 Clinical impacts
  • 08:31 The need for further investigation
  • 09:58 Limitations
  • 11:05 Further research
  • 13:08 Kalin interview
  • 13:21 Horan et al.
  • 17:34 Levenstein et al.
  • 19:00 Fountoulakis et al.
  • 20:57 Couture et al.
  • 23:18 Stern et al.
  • 27:35 McGirr et al.

Transcript

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