South Florida stunned the College Football world last week, beating Florida and HC Billy Napier in The Swamp. Should Mario Cristobal's Hurricanes be on alert?

On today's episode of Locked On College Football, Spencer McLaughlin and 'Locked On Buffs' host Kevin Borba discuss the changing at QB for Colorado. Is benching Kaidon Salter for Ryan Staub the right move by Deion Sanders?

USC travels to Purdue this week for its first Big 10 game of 2025. Lincoln Riley's Trojans should not have any problems with the upset-minded Boilermakers and 1st-year HC Barry Odom.

0:00 South Florida vs Miami preview

5:22 Miami's running game could be key

10:46 Quarterback chaos at Colorado

16:01 Colorado faces tough road test at Houston

22:26 Houston vs Colorado score predictions

25:50 Can Purdue upset USC at home?

30:07 Purdue's running game and offensive outlook

33:35 Final score predictions for USC-Purdue

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