IN this episode, Dr's J and Santhosh cover stories, studies, and general knowledge in their annual influenza special. Along the way they cover the poor decision making of the secretary for health and human services, the confluence of influenza and journal clubs, the original identification and discovery of the flu virus, a sneezy ferret, optimistic media, military vaccine testing, the discovery of seasonal flu changes, the art of flu surveillance, the damage done to surveillance by this administration, alternative vaccine production methods, dosing change recommendations and more! so sit back and catch some knowledge about whats coming to town!

Further Reading

https://utppublishing.com/doi/10.3138/jammi-2025-0025

https://www.cdc.gov/fluview/surveillance/2025-week-45.html

https://www.nejm.org/doi/full/10.1056/NEJMoa2416779?query=featured_home

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01742-8/abstract

https://www.ijidonline.com/article/S1201-9712(25)00322-4/fulltext

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In this episode Dr's J and Santhosh explore the history of off label prescribing of medications. Along the way they cover literature and the rise of food safety, the importance of legal phrasing, false statements versus false advertising, sulfanilamide tragedy of 1937, the creation of prescription and over the counter medications, the thalidomide scandal and the us physician who mostly prevented it, drug repurposing and some famous examples of off label uses for medication. So sit back and relax as we read the fine print on off label medications!

Further Reading

https://pmc.ncbi.nlm.nih.gov/articles/PMC8508135/#:~:text=Off%2Dlabel%20practice%20is%20a,scope%20of%20the%20marketing%20authorization.

chrome-extension://efaidnbmnnnibpcajpcglclefindmkaj/https://www.fda.gov/files/about%20fda/published/The-Sulfanilamide-Disaster.pdf

https://www.pharmacytimes.com/view/pharmacys-past-the-soothing-syrup-known-for-causing-death-in-thousands-of-babies-#:~:text=Mrs.,to%20kill%20the%20average%20child.

https://www.medrxiv.org/content/10.1101/2022.09.08.22279709v1.full

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In this episode, Dr's J and Santhosh explore some of the creative ways medical issues have been addressed throughout the years. Along the way they cover surprising uses for nun urine, a heart stopping utilization of saran wrap, the rebellious lumberjack who changed cardiology forever and a reason to flood one's anus with hydrogen. SO sit back and relax as we cover some unusal solutions to modern problems!

Further Reading

https://www.nytimes.com/1964/10/01/archives/public-cautioned-on-fertility-drug-distributor-says-pergonal-is-for.html

https://www.sciencedirect.com/science/article/pii/S0096558820314227?ref=pdf_download&fr=RR-2&rr=99c231cd4cd534ad

https://pmc.ncbi.nlm.nih.gov/articles/PMC1430651/

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In this episode, Dr Santhosh takes the lead and educates Dr J on some great moments in public health. Along the way they cover medical tongue twisters, staphylococcus, toxic shock syndrome, menstruation, superantigens, deadly tampons, disease surveillance, product testing group b strep and more! So sit back and relax as Dr Santhosh takes us on a journey of public health!

Further Reading

https://www.sciencedirect.com/science/article/pii/S0140673678922742

https://academic.oup.com/jid/article/145/4/458/862059

https://www.nejm.org/doi/10.1056/NEJM198012183032501

https://www.fda.gov/consumers/consumer-updates/facts-tampons-and-how-use-them-safely

https://pmc.ncbi.nlm.nih.gov/articles/PMC8540901/

https://www.cdc.gov/mmwr/preview/mmwrhtml/rr5910a1.htm

https://www.acog.org/clinical/clinical-guidance/committee-opinion/articles/2020/02/prevention-of-group-b-streptococcal-early-onset-disease-in-newborns

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In this episode, Dr's J and Santhosh dive into some studies and history of bodily fluids! Along the way they cover the crying classifications, tears on demand, the zone of inhibition, emotional leakage, limericks, the many suspected uses of saliva, recrements and excrements, congressional spittoons, fish sperm for wound healing, the science of sharts, harold and kumar go to whitecastle, and of course, the poop microbiome. So sit back and relax as we go all in on the things that come out of you!

Further Reading

https://www.inverse.com/innovation/fart-monitoring-ai

https://pmc.ncbi.nlm.nih.gov/articles/PMC7986284/

https://pmc.ncbi.nlm.nih.gov/articles/PMC6201288/

https://www.kjcls.org/journal/view.html?volume=50&number=2&spage=93#:~:text=Lysozyme%20is%20present%20in%20tears,ability%20to%20inhibit%20bacterial%20growth.

https://www.cell.com/cell-reports-medicine/fulltext/S2666-3791(24)00360-4

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In this episode Dr's J and Santhosh peer deep into the windows of the soul to talk about ophthalmology. Along the way they cover the bangles and forced parodies, the oldest ophthalmology doctor and monument, eye anatomy in the time of ancient Greece, cataract couching in ancient India, the invention of eyeglasses and their european influence, fathering a scientific field, oculists and secret societies in Germany, early textbooks, the history of prosthetic eyes, the creation of an entire new field of surgery and the surprising medical studies behind sunglasses. SO sit back and relax as we attempt not to blind you with science of eyesight!

Further Reading

https://pubmed.ncbi.nlm.nih.gov/17637502/

https://pmc.ncbi.nlm.nih.gov/articles/PMC10939838/#:~:text=Tinted%20lenses%20are%20one%20approach,but%20was%20not%20subjectively%20preferred.

https://pmc.ncbi.nlm.nih.gov/articles/PMC1772912/

https://www.warbyparker.com/learn/when-were-contacts-invented#:~:text=Plastic%20Contacts:%20A%20Revolution%20(1936,Contact%20Lenses%20Are%20Refined%20(1970s)

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In this episode, Dr's J and Santhosh once again perform their biweekly roundup of whats new in the medical world, this time with an emphasis on feel good research. Along the way they cover the intersection of Les Mis and the muppets, fat bear week, ozempic effects on imaging studies, xenotransplantation of the first pig liver, gene manipulation, full metal alchemist, innies v outies, the belly button biodiversity project, greek mythology, peripheral immunity and the nobel prize, the 2025 Ignoble award winners, and more! so sit back and relax as we teach you whats new in medical research!

Further Reading

https://www.researchsquare.com/article/rs-7514267/v1

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0329983

https://www.eurekalert.org/news-releases/1100522

https://linkinghub.elsevier.com/retrieve/pii/S0168827825024973

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In this episode Dr's J and Santhosh take on the talk about Tylenol! Along the way they cover some thoughts about the current health and human services secretary, the accidental discovery of a new fever reducer due to a pharmaceutical mix up, methemoglobinemia, brilliant marketing strategies, brand trivia, the Tylenol murders, the dinosaur link, the actual studies on Tylenol and autism, the memory fallacy, and more! So sit back and relax as we pop a couple chill pills to teach the truth about tylenol!

Further Reading

https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cssc.202400234

https://pmc.ncbi.nlm.nih.gov/articles/PMC8654482/

https://montrealgazette.com/opinion/columnists/the-right-chemistry-the-history-of-tylenol

chrome-extension://efaidnbmnnnibpcajpcglclefindmkaj/http://www.nancywest.net/pdfs/McNeilConsumerHealthcareCompany.pdf

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