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The Code Breaker

Jennifer Doudna, Gene Editing, and the Future of the Human Race

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The Code Breaker

Auteur(s): Walter Isaacson
Narrateur(s): Kathe Mazur, Walter Isaacson
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À propos de cet audio

A 2022 Audie Award Finalist

A Best Book of 2021 by Bloomberg BusinessWeek, Time, and The Washington Post

The bestselling author of Leonardo da Vinci and Steve Jobs returns with a “compelling” (The Washington Post) account of how Nobel Prize winner Jennifer Doudna and her colleagues launched a revolution that will allow us to cure diseases, fend off viruses, and have healthier babies.

When Jennifer Doudna was in sixth grade, she came home one day to find that her dad had left a paperback titled The Double Helix on her bed. She put it aside, thinking it was one of those detective tales she loved. When she read it on a rainy Saturday, she discovered she was right, in a way. As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.

Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his codiscovery of the structure of DNA. She and her collaborators turned a curiosity of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions.

The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code.

Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids?

After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020. Her story is an “enthralling detective story” (Oprah Daily) that involves the most profound wonders of nature, from the origins of life to the future of our species.

©2021 Walter Isaacson. All rights reserved. (P)2021 Simon & Schuster, Inc. All rights reserved. Femmes Professionnels et universitaires Science Science et technologie Sciences biologiques Technologie Médecine Du contenu qui fait réfléchir Future Technology
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Very well researched and delivered, with a good balance of the science and the human side of research.

Enjoyable and Informative

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I am a big fan of science books in general and of James Watson's The double helix.
I have read around 7 books by Walter Isaacson.

This was a great book on a subject (CRISPR) that is quite new, so I was happy to learn the fundamentals related to CRISPR.

As in most of its books, Walter Isaacson has a tendency to minimize the flaws of its main subject. But when you're aware of that, it's easy to enjoy the stories related to each character.

The decision to have the book narrated by Kathe Mazur was great choice, as the performance is excellent and having a feminine voice gets us closer to the main protagonists in the book.

Thanks

Learned good basics about CRISPR

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This book was a delicious listen! I can’t find anything negative to say about it. From the early days with her family I found myself wishing I had a Dad who was interested in science but I didn’t. Nonetheless, I somehow developed a pronounced interest in science and literature. Science won as I won a prestigious award to study in Britain. The all male lab were not supportive but they were unable to competently squash my desire to continue studying science
Long story short, I studied medicine going on to specialize in psychiatry. This is a very broad field of psychology from the bare-bones of brain function to the behavior of the individual with a particular brain. Examining how people write, for example is revealing in that context, This book should be read by anyone interested in science or those who are not sure.
Congratulations to the author on a fine piece of research well narrated and written.

The Code Breaker

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I didn’t believe a book could make me excited what progress man has made because of COVID-19. Thank you Jennifer Dowden and the other great. Scientists that such advancements possibly.

Great book

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This book opened my eyes to the possibilties of mRNA uses. I am now a firm believer in this technology and medical advancement.

Educate yourselves

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This book is arguably the best book I have read in many years. The author, being a non-scientist, was able to translate the highly technical science into understandable terms for the lay person. I am a biological scientist, with a general understanding of the DNA/RNA technology, although I have not done any lab bench work for more than 30 years (and obviously a lot has happened in this arena in that time), so much of this was new.

The central concepts were well explained and I appreciated how well the author took us through the pre-CRISPR days to our current situation with CoVid-19 The rivalry between scientists was well defined - along with the reminder that such rivalry provides incentive. I think that the current conviviality between scientists and the spirit of cooperation between individuals and institutions will sadly disappear after Covid has been arrested, but I hope I am wrong.

Overall, this was a most enjoyable read. I found myself going back to certain sections to listen once again, and will reread again and again.

Fabulously interesting, excellent narration

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Captivating modality especially for girls & women but also for all of us at any age.

Excellent narration pivotal story of our times

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This book show everything what any scientist and scholar should know become one of those position. Based on very good written journey masterpiece by Walter Issacson and great arit

Innovation journey Masterpiece

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I was fascinated and awed at some of the content. I learned a lot listening to this book.

An Interesting Listen

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Fascinating and eye opening read! I learned about so much more than I thought I would. Bio engineering is an issue that we all need to understand more about.

Eye opening!

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