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Bryan Johnson Podcast

Bryan Johnson Podcast

Auteur(s): Bryan Johnson
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The Bryan Johnson Podcast is ushering in a new era of being human. In this podcast I am joined by longevity physician Dr. Mike Mallin, my co-founder Kate Tolo, and the occasional guest. We discuss the science-based protocol to help you become your best self. After living in Ecuador for two years among extreme poverty at the age of 21, I returned to the US and devoted my life to making the largest and most meaningful impact on humanity. After selling my company Braintree Venmo for $800 million, I traveled back in time to my 21 year old dreams of doing something impactful for the human race. I wondered if we may be the first generation to not die. I put together a team of 30 medical professionals and built the world’s best health protocol, Blueprint. On this protocol, I became the most biologically measured person in history and achieved the best biomarkers in the world, quantitatively becoming the healthiest person on the planet. Now is the first time in 2,000 years that a new, globally adopted ideology must emerge. AI is progressing faster than any of us can comprehend, causing us to reexamine everything we think about ourselves, each other, and society. This is now humanity’s to-do list: Don’t die individually. Don’t kill each other. Don’t destroy the planet. Align AI with Don’t Die. Join us on this journey. New episodes releasing weekly. Hygiène et mode de vie sain Science
Épisodes
  • Psilocybin, LSD & Marijuana: Ranking Drugs for Longevity (Part 2)
    Sep 11 2025
    Should I try shrooms for science? In part two of three of our series investigating drugs for longevity, I’m putting psilocybin, LSD and DMT under the microscope - and revealing some pretty exciting research that connects psychedelics to longer lifespans. We’ll also talk about weed, and what the data says about marijuana for longevity. Study Links: Psilocybin for Cancer Patients LSD: Longevity in Worms Cannabis Use Disorder Increases Mortality Risk Marijuana Increases Epigenetic Aging Marijuana’s Impacts on Sleep Improving Sleep with Medical Cannabis Hosts: Bryan Johnson: Blueprint Founder Kate Tolo: Blueprint Co-Founder Dr. Mike Mallin: Lead Physician for Bryan Johnson Connect: X: https://x.com/bryan_johnson YouTube: https://www.youtube.com/@BryanJohnson Instagram: https://www.instagram.com/bryanjohnson TikTok: https://www.tiktok.com/@_bryan_johnson_ Chapters: 00:00 - Introduction 01:52 - First Experiences With Drugs 05:42 - Psychedelics in Society 13:29 - Psilocybin, LSD & DMT 34:35 - Marijuana 50:53 - Longevity Rankings
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    56 min
  • Ketamine & Cocaine: Ranking Drugs for Longevity (Part 1)
    Sep 4 2025
    Can doing lines help you live longer? That depends on what you’re taking. In this three-part series, I’m ranking drugs based on their ties to longevity, starting with ketamine and cocaine. I tested ketamine on myself to study its impacts on the brain — here’s what we found. Study Links: Ketamine’s Effects on Epigenetic Age Extending Ketamine’s Therapeutic Window Ibogaine Therapy for PTSD Hosts: Bryan Johnson: Blueprint Founder Kate Tolo: Blueprint Co-Founder Dr. Mike Mallin: Lead Physician for Bryan Johnson Connect: X: https://x.com/bryan_johnson YouTube: https://www.youtube.com/@BryanJohnson Instagram: https://www.instagram.com/bryanjohnson TikTok: https://www.tiktok.com/@_bryan_johnson_ Chapters: 00:00 - Introduction 03:14 - Social Norms Around Drugs 08:59 - Psychedelics as Therapy: Overview 10:20 - Cocaine 17:15 - Fentanyl Dangers 23:27 - Ketamine: Brain Impacts + Longevity 41:29 - Measuring The Impacts of Psychedelics 47:51 - Longevity Rankings: Cocaine + Ketamine
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    50 min
  • Jesse James West on AI, Fitness & Self-Worth
    Aug 28 2025
    Fitness creator Jesse James West is a natural bodybuilder who makes some of the coolest videos on YouTube for over 7 million subscribers. We’re talking about his motto of “stay relentless,” and how he balances work, health and life now that he’s newly married. Plus, he shares about the time that he also had a breakdown in Target - and how it may have saved his life. Connect with Bryan: X: https://x.com/bryan_johnson YouTube: https://www.youtube.com/@BryanJohnson Instagram: https://www.instagram.com/bryanjohnson TikTok: https://www.tiktok.com/@_bryan_johnson_ Connect with Jesse: YouTube: https://www.youtube.com/@JesseJamesWest Instagram: https://www.instagram.com/jessejameswest TikTok: https://www.tiktok.com/@jessejameswest X: https://x.com/jessejameswestt Chapters: 00:00:00 - Introduction 00:01:15 - Finding Work Life Balance 00:08:32 - Stay Relentless 00:11:01 - Jesse’s Darkest Moment + What He Learned 00:22:48 - What an AI Future Looks Like 00:27:24 - Jesse’s Health Protocol 00:34:26 - Longevity, Psychedelics, & Aliens 00:44:58 - Married Life + Family Planning 00:48:55 - Top Tips for Longevity 00:54:02 - Bodybuilding, Steroids, & Healthy Eating 00:57:23 - Jet Lag Protocol 00:59:32 - Living For Tomorrow = Living Forever 01:02:45 - Jesse’s Health Goals
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    1 h et 4 min
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