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The Metabolic Link

Written by: Dr. Dominic D'Agostino PhD Dr. Angela Poff PhD and Victoria Field
  • Summary

  • Welcome to The Metabolic Link, a medical and science podcast that explores the common thread of metabolism in health and disease. Join Dr. Dominic D'Agostino PhD, Dr. Angela Poff PhD, and Victoria Field as they dive into the latest research on metabolic health and therapy alongside some of the world’s leading experts. They'll also discuss how this science is being applied in the real world. This is where science meets society.
    © 2024 The Metabolic Link
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Episodes
  • A Biological Switch that Drives Obesity, Diabetes, and Dementia with Richard Johnson, MD | The Metabolic Link Ep. 39
    Apr 23 2024

    Become a member of The Metabolic Initiative for exclusive episodes and to earn CMEs

    In this episode, recorded at Metabolic Health Summit 2024, Dr. Richard Johnson dives into the groundbreaking research that has uncovered the central role of fructose in driving the epidemics of obesity, diabetes, and a wide range of other metabolic diseases.

    Dr. Johnson presents compelling evidence that fructose, a seemingly innocuous sugar, is in fact a key trigger for activating a powerful biological survival switch. This switch, evolved in nature to help animals prepare for times of scarcity, is now being inadvertently activated in humans by our modern high-carbohydrate, high-sugar diets.

    Through detailed scientific explanation and insightful case studies, Dr. Johnson illuminates how fructose's unique metabolic effects - including its ability to lower ATP levels, induce leptin resistance, and promote fat storage - are the driving forces behind the rise of metabolic syndrome and its associated conditions.

    Equally important, Dr. Johnson offers practical dietary recommendations and strategies to help individuals navigate this complex landscape, emphasizing the importance of reducing sugar, refined carbs, and processed foods, while embracing a low-carb, nutrient-dense approach.

    This eye-opening episode is a must-listen for anyone seeking to understand the root causes of the metabolic health crisis and learn evidence-based solutions to reclaim their wellbeing.

    Special thanks to our sponsors:

    Genova Connect, powered by Genova Diagnostics, offers easy access to advanced lab tests, covering key health areas like metabolic health, nutrition, gut health, immune function, and hormones. Receive 15% off any of their tests with code metaboliclink: http://gdx.net/themetaboliclink

    LMNT, a zero-sugar electrolyte drink mix free of artificial colors and dodgy ingredients. Get a free LMNT Sample Pack with any drink mix purchase at: drinkLMNT.com/MetabolicLink

    In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!

    You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel, Apple, Google, Spotify, Amazon Music, and Buzzsprout.

    Thanks for listening! Follow us on social media @metabolichealthsummit for the latest science on metabolic health and therapy. Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

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    55 mins
  • Journal Club: Exploring Immune Response to Diet: Vegan vs Ketogenic Ep. 38
    Apr 9 2024

    In this episode of The Metabolic Link, Victoria Field, Dr. Dominic D'Agostino, and Dr. Angela Poff dive into a fascinating new paper that compares the metabolic and immune impacts of ketogenic and vegan diets in humans.

    The study, titled “Differential Peripheral Immune Signatures Elicited by Vegan Versus Ketogenic Diets in Humans” takes a deep dive into the multi-omic effects of these two very different dietary approaches. The researchers found that just two weeks on a ketogenic diet significantly enhanced markers of adaptive immunity, while the vegan diet was associated with increased innate immune function.

    The hosts unpack these findings, discussing the potential mechanisms behind the divergent immune signatures, the limitations of the short-term study design, and the need for further research.

    They also highlight the importance of carefully standardizing the macronutrient and micronutrient compositions of the dietary interventions to isolate the key drivers of the observed changes.

    Overall, this episode provides a thought-provoking look at the profound impacts that diet can have on the functioning of our immune system, setting the stage for future studies exploring the therapeutic potential of nutritional approaches.

    This episode is sponsored by Genova Diagnostics. Genova has been researching and refining precision health testing for decades. It's that experience that has allowed them to create comprehensive assessments that shed light on your individual health status and make recommendations for changes that will bring your wellness into focus.

    Genova Connect, powered by Genova Diagnostics, offers easy access to advanced lab tests, covering key health areas like metabolic health, nutrition, gut health, immune function, and hormones. Through Genova Connect, anyone can gain insights into their health and find ways to improve their well-being. Learn more at https://gdx.net/themetaboliclink

    As mentioned in the introduction, you can watch the free virtual masterclass co-hosted Genova Diagnostics and Metabolic Health Summit showcasing some of the world-leading experts in metabolic health here

    In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!

    You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel, Apple, Google, Spotify, Amazon Music, and Buzzsprout.

    Thanks for listening! Follow us on social media @metabolichealthsummit for the latest science on metabolic health and therapy. Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

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    51 mins
  • BioMolecular Athlete: Advanced Tools For Enhanced Human Performance with Andy Galpin, PhD | The Metabolic Link Ep. 37
    Mar 26 2024

    The following Metabolic Link episode was originally filmed at Metabolic Health Summit 2024 and we're excited to share it with you today in its entirety! In this presentation, Dr. Andy Galpin, a human performance scientist, shares his insights on utilizing scientific principles, specifically the 'Biomolecular Athlete' concept, to achieve athletic excellence. He emphasizes the importance of individualized strategies that consider sleep, diet, stress, respiratory rates, and blood chemistry.

    The discussion then progresses to the groundbreaking future of human performance, including the use of digital twins for simulating and optimizing individual health outcomes, and the exploration of advanced technologies such as in-mouth sensors, full-body MRI, shoe sole force plates, and markerless motion capture.

    Case studies are presented to illustrate the successful application of these innovative approaches, showcasing the potential for precision and customization in coaching for optimal health and performance.

    This talk is sponsored by Genova Diagnostics. Genova has been researching and refining precision health testing for decades. It's that experience that has allowed them to create comprehensive assessments that shed light on your individual health status and make recommendations for changes that will bring your wellness into focus.

    Genova Connect, powered by Genova Diagnostics, offers easy access to advanced lab tests, covering key health areas like metabolic health, nutrition, gut health, immune function, and hormones. Through Genova Connect, anyone can gain insights into their health and find ways to improve their well-being. Learn more at gdx.net/themetaboliclink

    As mentioned in the introduction, you can watch this free virtual masterclass co-hosted Genova Diagnostics and Metabolic Health Summit showcasing some of the world-leading experts in metabolic health.

    In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!

    You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel, Apple, Google, Spotify, Amazon Music, and Buzzsprout.

    Thanks for listening! Follow us on social media @metabolichealthsummit for the latest science on metabolic health and therapy. Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

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    1 hr and 29 mins

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