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Meet Charlie; unfulfilled and perimenopausal, Charlie’s suburban life is a far cry from the Manhattan glamour she once dreamed of. Her husband is incapable of talking about anything other than his latest Ironman challenge, her sex life consists of fictional encounters with Hollywood stars, her kids need constant man-management, and to make things worse, her optician has just prescribed her reading glasses. Oh, and she can’t stop crying at TV adverts… In the hope of re-discovering her sense of self, Charlie begins writing a list: 45 things to do before she’s 45.

Featuring a mix of award-winning comedians and newcomers to the scene, there's something for everyone, from stand-up to sketches, satire, songs and poems - with a few surprises thrown in. And if you don't like any of the acts, well...another will be along in about 55 seconds. Presiding over this comedy maelstrom is John Humphrys (the fierce one from the Today programme), who sits at the side of the stage with a stopwatch, ready to cut the microphone when the time is up.

Jane is trying. She's been trying for a baby, with increasing desperation as her 30s sail by. Now, she's trying to make a new start back home with her overprotective, charades-obsessed parents—having left her career and cheating fiancé behind in London. With an increasing load on her plate, friends and family who think she'll have a perfect life if she only listens to them, and a brain which questions every decision she's ever made, can Jane conquer her demons and step forward on her own?

Isy woke up one day in her late 20s to discover that the invisible deal she'd done with her best mates - that they'd prolong growing up for as long as possible - had all been in her head. Everyone around her is suddenly into mortgages, farmers' markets and nappies rather than the idea of running naked into the sea or getting hammered in Plymouth with 80-year-old men.

Isy Suttie is our guide to all things love-related in these five fantastic series. Come with her as she shares her relationship stories, talks about the couples she's tried to bring together, evokes bittersweet memories of her childhood and adolescence, and shares a couple of the weird and wonderful things that give her pleasure.